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Details on Person PI is phosphorylated to PI4P by PI4K2A/B at the early endosome membrane

Class:Id	Reaction:1675974
_displayName	PI is phosphorylated to PI4P by PI4K2A/B at the early endosome membrane
_doRelease	TRUE
_timestamp	2012-05-31 09:38:02
authored	[InstanceEdit:1678579] Williams, MG, 2011-10-18
catalystActivity	[CatalystActivity:1806244] 1-phosphatidylinositol 4-kinase activity of PI4K2A/2B [cytosol]
compartment	[Compartment:171062] early endosome membrane [Compartment:70101] cytosol
created	[InstanceEdit:1676083] Williams, MG, 2011-10-17
edited	[InstanceEdit:1482514] Williams, MG, 2011-08-12
input	[SimpleEntity:113592] ATP [cytosol] [SimpleEntity:1806199] PI [early endosome membrane]
isChimeric	FALSE
literatureReference	[LiteratureReference:1676091] Characterization of type II phosphatidylinositol 4-kinase isoforms reveals association of the enzymes with endosomal vesicular compartments
modified	[InstanceEdit:1678578] Williams, MG, 2011-10-18 [InstanceEdit:1806251] Williams, MG, 2011-10-24 [InstanceEdit:1967225] Williams, MG, 2011-11-04 [InstanceEdit:2247961] D'Eustachio, P, 2012-05-14 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	PI is phosphorylated to PI4P by PI4K2A/B at the early endosome membrane
output	[SimpleEntity:29370] ADP [cytosol] [SimpleEntity:1806180] PI4P [early endosome membrane]
precedingEvent	[Reaction:1676141] PI3P is dephosphorylated to PI by MTM proteins at the early endosome membrane [Homo sapiens] [Reaction:1676162] PI(3,4)P2 is dephosphorylated to PI3P by INPP4A/B at the early endosome membrane [Homo sapiens] [Reaction:1676174] PI(3,5)P2 is dephosphorylated to PI3P by FIG4 at the early endosome membrane [Homo sapiens] [Reaction:1675939] PI is phosphorylated to PI3P by PIK3C2A/3 at the early endosome membrane [Homo sapiens]
releaseDate	2012-06-12
reviewed	[InstanceEdit:2247963] Wakelam, Michael, 2012-05-14
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:2294666] R-HSA-1675974.2
summation	[Summation:1676089] At the early endosome membrane, phosphatidylinositol 4-kinas...
(hasEvent)	[Pathway:1660516] Synthesis of PIPs at the early endosome membrane [Homo sapiens]
(precedingEvent)	[Reaction:1676206] PI4P is phosphorylated to PI(3,4)P2 by PIK3C2A at the early endosome membrane [Homo sapiens]
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No pathways have been reviewed or authored by PI is phosphorylated to PI4P by PI4K2A/B at the early endosome membrane (1675974)