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Details on Person Association of Tat:P-TEFb(Cyclin T1:Cdk9) with the TAR sequence

Class:Id	Reaction:167239
_displayName	Association of Tat:P-TEFb(Cyclin T1:Cdk9) with the TAR sequence
_doRelease	FALSE
_timestamp	2016-07-15 23:49:47
authored	[InstanceEdit:165064] Matthews, L, Rice, AP, 2005-07-27 00:00:00
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:167240] Matthews, L, 2005-10-13 20:09:16
edited	[InstanceEdit:165066] Matthews, L, 2005-07-26 23:29:22
input	[Complex:167078] DSIF:NELF:early elongation complex [nucleoplasm] [Homo sapiens] [Complex:167237] Tat:P-TEFb(Cyclin T1:Cdk9) complex [nucleoplasm] [Homo sapiens]
literatureReference	[LiteratureReference:167873] A novel CDK9-associated C-type cyclin interacts directly with HIV-1 Tat and mediates its high-affinity, loop-specific binding to TAR RNA
modified	[InstanceEdit:167455] Matthews, L, 2005-10-18 10:45:57 [InstanceEdit:167802] Matthews, L, 2005-11-09 01:30:34 [InstanceEdit:167875] Matthews, L, 2005-11-09 23:23:14 [InstanceEdit:169296] Vastrik, I, 2005-11-28 11:33:22 [InstanceEdit:170181] Gopinathrao, G, 2005-12-27 21:08:53 [InstanceEdit:170768] Matthews, L, 2006-01-15 13:04:15 [InstanceEdit:170793] Vastrik, I, 2006-01-16 05:24:48 [InstanceEdit:178121] Gopinathrao, G, 2006-04-17 16:19:43 [InstanceEdit:2671732] D'Eustachio, P, 2012-11-23 [InstanceEdit:5621512] Matthews, Lisa, 2014-08-29 [InstanceEdit:8879177] Wu, G, 2016-07-15
name	Association of Tat:P-TEFb(Cyclin T1:Cdk9) with the TAR sequence
output	[Complex:167241] Tat-containing DSIF:NELF:early elongation complex [nucleoplasm] [Homo sapiens]
precedingEvent	[Reaction:167085] Formation of DSIF:NELF:HIV-1 early elongation complex [Homo sapiens] [Reaction:112437] Formation of NELF complex [Homo sapiens] [Reaction:167083] DSIF complex binds to RNA Pol II (hypophosphorylated) [Homo sapiens] [Reaction:167234] Association of Tat with P-TEFb(Cyclin T1:Cdk9) [Homo sapiens] [Reaction:167235] Formation of the P-TEFb(Cyclin T1:Cdk9) complex [Homo sapiens]
relatedSpecies	[Species:164493] Human immunodeficiency virus 1
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:8903966] R-HSA-167239.1
summation	[Summation:167876] Tat associates with the T1 subunit of P-TEFb(Cyclin T1:Cdk9)...
(precedingEvent)	[Reaction:167191] Hyperphosphorylation (Ser2) of RNA Pol II CTD by the P-TEFb(Cyclin T1:Cdk9) complex [Homo sapiens]
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No pathways have been reviewed or authored by Association of Tat:P-TEFb(Cyclin T1:Cdk9) with the TAR sequence (167239)