Reactome: A Curated Pathway Database
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Query author contributions in Reactome

Reactome depends on collaboration between our curation team and outside experts to assemble and peer-review its pathway modules. The integration of ORCID within Reactome enables us to meet a key challenge with authoring, curating and reviewing biological information by incentivizing and crediting the external experts that contribute their expertise and time to the Reactome curation process. More information is available at ORCID and Reactome.

If you have an ORCID ID that is not listed on this page, please forward this information to us and we will update your Reactome pathway records.

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Details on Person RAF1 [cytosol]

Class:IdEntityWithAccessionedSequence:167205
_displayNameRAF1 [cytosol]
_timestamp2012-12-03 13:38:35
compartment[Compartment:70101] cytosol
created[InstanceEdit:167212] 2006-02-07 08:34:20
endCoordinate648
modified[InstanceEdit:169286] Jassal, Bijay, 2005-11-28
[InstanceEdit:197531] Jassal, B, 2007-05-14 10:34:26
[InstanceEdit:198429] Jassal, B, 2007-06-19 12:45:26
[InstanceEdit:198768] Jassal, B, 2007-06-29 08:05:28
[InstanceEdit:2682357] Jassal, Bijay, 2012-11-29
[InstanceEdit:2684910] Jassal, Bijay, 2012-12-03
[InstanceEdit:3132750] Wu, G, 2013-02-13
nameRAF1
C-Raf
referenceEntity[ReferenceGeneProduct:58255] UniProt:P04049 RAF1 [Homo sapiens]
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:1109761] R-HSA-167205.1
startCoordinate1
(hasComponent)[Complex:167219] Raf1 (Zn++ cofactor) [cytosol] [Homo sapiens]
[Complex:197507] Raf-1:Phospho-RKIP [cytosol] [Homo sapiens]
[Complex:197525] RAF:MEK [cytosol] [Homo sapiens]
[Complex:197540] RAF:RKIP [cytosol] [Homo sapiens]
[Complex:430243] Rap1-GTP:Raf1 [plasma membrane] [Homo sapiens]
[Complex:443443] Active c-Src:Raf1 [cytosol] [Homo sapiens]
[Complex:443827] 14-3-3-zeta:Raf1 [cytosol] [Homo sapiens]
[Complex:2682342] RAF1:SGK:TSC22D3:WPP [cytosol] [Homo sapiens]
[Complex:5624478] p21 RAS:GTP:RAF1 [plasma membrane] [Homo sapiens]
[Complex:9732727] IFNG:p-IFNGR1:p-JAK1:IFNGR2:p-JAK2:RAF1 [plasma membrane] [Homo sapiens]
(input)[Reaction:167222] Ras-GTP recruits Raf [Homo sapiens]
[Reaction:197502] ERK directly phosphorylates RAF, providing positive feedback [Homo sapiens]
[Reaction:209343] Human PKA phosphorylates RAF1 in the vicinity of its C1 domain [Homo sapiens]
[Reaction:392835] Rap1 sequesters Raf1 to inhibit ERK cascade [Homo sapiens]
[Reaction:443439] c-Src binds Raf1 [Homo sapiens]
[Reaction:443831] 14-3-3-zeta binds Raf1 [Homo sapiens]
[Reaction:5624494] RAF1 binds p21 RAS:GTP [Homo sapiens]
[Reaction:9732729] Activated JAK1 binds RAF1 [Homo sapiens]
(output)[Reaction:197482] Phospho-RKIP is released from RAF, contributing to a positive feedback [Homo sapiens]
[Reaction:197542] Phospho-RKIP is released from RAF, contributing to a positive feedback [Rattus norvegicus]
(updatedInstance)[_UpdateTracker:9876530] Update Tracker - [EntityWithAccessionedSequence:167205] RAF1 [cytosol] - v44:[modifyEndCoordinate, modifyName]
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No pathways have been reviewed or authored by RAF1 [cytosol] (167205)