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Details on Person Addition of nucleotides 5 through 9 on the growing HIV-1 transcript

Class:Id	Reaction:167136
_displayName	Addition of nucleotides 5 through 9 on the growing HIV-1 transcript
_doRelease	TRUE
_timestamp	2021-11-03 19:06:17
authored	[InstanceEdit:165064] Matthews, L, Rice, AP, 2005-07-27 00:00:00
catalystActivity	[CatalystActivity:109910] DNA-directed RNA polymerase activity of RNA Polymerase II (unphosphorylated):TFIIF complex [nucleoplasm]
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:167126] Matthews, L, 2005-10-11 08:30:05
disease	[Disease:1660559] Human immunodeficiency virus infectious disease
edited	[InstanceEdit:165066] Matthews, L, 2005-07-26 23:29:22
inferredFrom	[Reaction:75873] Addition of Nucleotides 5 through 9 on the growing Transcript [Homo sapiens]
input	[Complex:167124] HIV-1 transcription complex containing 4 nucleotide long transcript [nucleoplasm] [Homo sapiens] [SimpleEntity:9757634] NTP [nucleoplasm] [SimpleEntity:9757634] NTP [nucleoplasm] [SimpleEntity:9757634] NTP [nucleoplasm] [SimpleEntity:9757634] NTP [nucleoplasm] [SimpleEntity:9757634] NTP [nucleoplasm]
literatureReference	[LiteratureReference:111276] A role for TFIIH in controlling the activity of early RNA polymerase II elongation complexes. [LiteratureReference:110389] Recycling of the general transcription factors during RNA polymerase II transcription. [LiteratureReference:111275] Strong natural pausing by RNA polymerase II within 10 bases of transcription start may result in repeated slippage and reextension of the nascent RNA. [LiteratureReference:110387] Three transitions in the RNA polymerase II transcription complex during initiation.
modified	[InstanceEdit:167258] Matthews, L, 2005-10-13 20:50:19 [InstanceEdit:167325] Matthews, L, 2005-10-15 11:51:25 [InstanceEdit:169296] Vastrik, I, 2005-11-28 11:33:22 [InstanceEdit:170174] Gopinathrao, G, 2005-12-25 02:17:30 [InstanceEdit:170793] Vastrik, I, 2006-01-16 05:24:48 [InstanceEdit:2671731] D'Eustachio, P, 2012-11-23 [InstanceEdit:3632906] Gillespie, ME, 2013-05-28 [InstanceEdit:5621512] Matthews, Lisa, 2014-08-29 [InstanceEdit:6787528] D'Eustachio, Peter, 2015-07-14 [InstanceEdit:8946993] Shorser, Solomon, 2016-11-07 [InstanceEdit:9757642] D'Eustachio, Peter, 2021-11-03 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	Addition of nucleotides 5 through 9 on the growing HIV-1 transcript
output	[Complex:109629] TFIIA [nucleoplasm] [Homo sapiens] [Complex:109626] TFIID [nucleoplasm] [Homo sapiens] [Complex:109633] TFIIE [nucleoplasm] [Homo sapiens] [SimpleEntity:113541] PPi [nucleoplasm] [SimpleEntity:113541] PPi [nucleoplasm] [SimpleEntity:113541] PPi [nucleoplasm] [SimpleEntity:113541] PPi [nucleoplasm] [SimpleEntity:113541] PPi [nucleoplasm] [Complex:167100] HIV-1 transcription complex containing 9 nucleotide long transcript [nucleoplasm] [Homo sapiens]
precedingEvent	[BlackBoxEvent:167113] Addition of the fourth nucleotide on the nascent HIV-1 transcript: Second Transition [Homo sapiens] [BlackBoxEvent:9613490] Unwinding of DNA for the nascent HIV-1 transcript: Second Transition [Homo sapiens]
relatedSpecies	[Species:164493] Human immunodeficiency virus 1
releaseDate	2005-04-11
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:360502] R-HSA-167136.5
summation	[Summation:111277] Formation of the second phosphodiester bond creates a 3-nt p...
(hasEvent)	[Pathway:167162] RNA Polymerase II HIV Promoter Escape [Homo sapiens]
(precedingEvent)	[Reaction:167117] Addition of nucleotides 10 and 11 on the growing HIV-1 transcript: Third Transition [Homo sapiens] [Reaction:167468] Abortive HIV-1 Initiation After Second Transition [Homo sapiens]
(updatedInstance)	[_UpdateTracker:9775442] Update Tracker - [Reaction:167136] Addition of nucleotides 5 through 9 on the growing HIV-1 transcript - v79:[add_removeInput] [_UpdateTracker:9782566] Update Tracker - [Reaction:167136] Addition of nucleotides 5 through 9 on the growing HIV-1 transcript - v59:[modifyText] [_UpdateTracker:9783008] Update Tracker - [Reaction:167136] Addition of nucleotides 5 through 9 on the growing HIV-1 transcript - v57:[modifyText] [_UpdateTracker:9784335] Update Tracker - [Reaction:167136] Addition of nucleotides 5 through 9 on the growing HIV-1 transcript - v54:[addLiteratureReference] [_UpdateTracker:9784568] Update Tracker - [Reaction:167136] Addition of nucleotides 5 through 9 on the growing HIV-1 transcript - v53:[modifyText] [_UpdateTracker:9789537] Update Tracker - [Reaction:167136] Addition of nucleotides 5 through 9 on the growing HIV-1 transcript - v37:[modifyText]
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