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Details on Person Newly formed phosphodiester bond stabilized and PPi released

Class:Id	Reaction:167134
_displayName	Newly formed phosphodiester bond stabilized and PPi released
_doRelease	TRUE
_timestamp	2016-11-10 00:54:37
authored	[InstanceEdit:165064] Matthews, L, Rice, AP, 2005-07-27 00:00:00
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:167126] Matthews, L, 2005-10-11 08:30:05
disease	[Disease:1660559] Human immunodeficiency virus infectious disease
edited	[InstanceEdit:165066] Matthews, L, 2005-07-26 23:29:22
inferredFrom	[Reaction:75864] Newly Formed Phosphodiester Bond Stabilized and PPi Released [Homo sapiens]
input	[Complex:167106] HIV-1 initiation complex with phosphodiester-PPi intermediate [nucleoplasm] [Homo sapiens]
literatureReference	[LiteratureReference:110387] Three transitions in the RNA polymerase II transcription complex during initiation.
modified	[InstanceEdit:167372] Matthews, L, 2005-10-15 14:27:53 [InstanceEdit:169296] Vastrik, I, 2005-11-28 11:33:22 [InstanceEdit:170174] Gopinathrao, G, 2005-12-25 02:17:30 [InstanceEdit:170793] Vastrik, I, 2006-01-16 05:24:48 [InstanceEdit:2671734] D'Eustachio, P, 2012-11-23 [InstanceEdit:3632906] Gillespie, ME, 2013-05-28 [InstanceEdit:5621512] Matthews, Lisa, 2014-08-29 [InstanceEdit:6787507] D'Eustachio, Peter, 2015-07-13 [InstanceEdit:8946993] Shorser, Solomon, 2016-11-07 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	Newly formed phosphodiester bond stabilized and PPi released
output	[SimpleEntity:113541] PPi [nucleoplasm] [Complex:167101] HIV-1 transcription complex [nucleoplasm] [Homo sapiens]
precedingEvent	[Reaction:167130] Nucleophillic attack by 3'-hydroxyl oxygen of nascent HIV-1 transcript on the Alpha phosphate of NTP [Homo sapiens] [Reaction:167118] NTP binds active site of RNA Polymerase II in HIV-1 open pre-initiation complex [Homo sapiens]
relatedSpecies	[Species:164493] Human immunodeficiency virus 1
releaseDate	2005-06-13
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:361846] R-HSA-167134.4
summation	[Summation:178969] At the beginning of this reaction, 1 molecule of 'HIV-1 init...
(hasEvent)	[Pathway:167161] HIV Transcription Initiation [Homo sapiens]
(precedingEvent)	[Reaction:167477] Abortive HIV-1 initiation after formation of the first phosphodiester bond [Homo sapiens] [BlackBoxEvent:9613498] Unwinding of DNA for the nascent HIV-1 transcript [Homo sapiens]
(updatedInstance)	[_UpdateTracker:9784058] Update Tracker - [Reaction:167134] Newly formed phosphodiester bond stabilized and PPi released - v54:[addLiteratureReference]
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