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Details on Person Addition of nucleotides between position +11 and +30 on HIV-1 transcript

Class:Id	Reaction:167115
_displayName	Addition of nucleotides between position +11 and +30 on HIV-1 transcript
_doRelease	TRUE
_timestamp	2021-11-03 18:03:49
authored	[InstanceEdit:165064] Matthews, L, Rice, AP, 2005-07-27 00:00:00
catalystActivity	[CatalystActivity:109910] DNA-directed RNA polymerase activity of RNA Polymerase II (unphosphorylated):TFIIF complex [nucleoplasm]
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:167126] Matthews, L, 2005-10-11 08:30:05
disease	[Disease:1660559] Human immunodeficiency virus infectious disease
edited	[InstanceEdit:165066] Matthews, L, 2005-07-26 23:29:22
inferredFrom	[Reaction:111264] Addition of nucleotides between position +11 and +30 [Homo sapiens]
input	[Complex:167132] HIV-1 transcription complex containing 11 nucleotide long transcript [nucleoplasm] [Homo sapiens] [SimpleEntity:9757634] NTP [nucleoplasm]
literatureReference	[LiteratureReference:111265] Analysis of the open region of RNA polymerase II transcription complexes in the early phase of elongation. [LiteratureReference:111266] Promoter clearance by RNA polymerase II is an extended, multistep process strongly affected by sequence. [LiteratureReference:111267] Promoter escape by RNA polymerase II. Formation of an escape-competent transcriptional intermediate is a prerequisite for exit of polymerase from the promoter. [LiteratureReference:110389] Recycling of the general transcription factors during RNA polymerase II transcription.
modified	[InstanceEdit:167260] Matthews, L, 2005-10-13 20:51:36 [InstanceEdit:167326] Matthews, L, 2005-10-15 11:51:59 [InstanceEdit:169296] Vastrik, I, 2005-11-28 11:33:22 [InstanceEdit:170174] Gopinathrao, G, 2005-12-25 02:17:30 [InstanceEdit:170793] Vastrik, I, 2006-01-16 05:24:48 [InstanceEdit:2671731] D'Eustachio, P, 2012-11-23 [InstanceEdit:3632906] Gillespie, ME, 2013-05-28 [InstanceEdit:5621512] Matthews, Lisa, 2014-08-29 [InstanceEdit:6787507] D'Eustachio, Peter, 2015-07-13 [InstanceEdit:8946993] Shorser, Solomon, 2016-11-07 [InstanceEdit:9757638] D'Eustachio, Peter, 2021-11-03 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	Addition of nucleotides between position +11 and +30 on HIV-1 transcript
output	[SimpleEntity:113541] PPi [nucleoplasm] [Complex:167120] HIV-1 transcription complex containing transcript to +30 [nucleoplasm] [Homo sapiens]
precedingEvent	[Reaction:167117] Addition of nucleotides 10 and 11 on the growing HIV-1 transcript: Third Transition [Homo sapiens] [Reaction:167136] Addition of nucleotides 5 through 9 on the growing HIV-1 transcript [Homo sapiens]
relatedSpecies	[Species:164493] Human immunodeficiency virus 1
releaseDate	2006-01-23
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:358236] R-HSA-167115.5
summation	[Summation:111268] RNA polymerase II transcription complexes are susceptible to...
(hasEvent)	[Pathway:167162] RNA Polymerase II HIV Promoter Escape [Homo sapiens]
(precedingEvent)	[Reaction:167111] Extrusion of 5'-end of 30 nt long HIV-1 transcript through the pore in Pol II complex [Homo sapiens]
(updatedInstance)	[_UpdateTracker:9775324] Update Tracker - [Reaction:167115] Addition of nucleotides between position +11 and +30 on HIV-1 transcript - v79:[add_removeInput] [_UpdateTracker:9784141] Update Tracker - [Reaction:167115] Addition of nucleotides between position +11 and +30 on HIV-1 transcript - v54:[addLiteratureReference]
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