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Details on Person HIV Promoter Opening: First Transition
Class:Id Reaction:167097
_displayName HIV Promoter Opening: First Transition
_doRelease TRUE
_timestamp 2016-11-10 00:55:45
authored [InstanceEdit:165064] Matthews, L, Rice, AP, 2005-07-27 00:00:00
catalystActivity [CatalystActivity:109879] 3'-5' DNA helicase activity of TFIIH [nucleoplasm]
compartment [Compartment:7660] nucleoplasm
created [InstanceEdit:167126] Matthews, L, 2005-10-11 08:30:05
disease [Disease:1660559] Human immunodeficiency virus infectious disease
edited [InstanceEdit:165066] Matthews, L, 2005-07-26 23:29:22
inferredFrom
input [SimpleEntity:29358] ATP [nucleoplasm] [Complex:167125] HIV-1 closed pre-initiation complex [nucleoplasm] [Homo sapiens]
literatureReference [LiteratureReference:111269] Polymerase II promoter activation: closed complex formation and ATP-driven start site opening. [LiteratureReference:110387] Three transitions in the RNA polymerase II transcription complex during initiation. [LiteratureReference:110388] Transcription factors IIE and IIH and ATP hydrolysis direct promoter clearance by RNA polymerase II. [LiteratureReference:111270] DNA topology and a minimal set of basal factors for transcription by RNA polymerase II. [LiteratureReference:111271] Peeling by binding or twisting by cranking: models for promoter opening and transcription initiation by RNA polymerase II. [LiteratureReference:110385] The general transcription factors of RNA polymerase II. [LiteratureReference:111272] Reconstitution of the transcription factor TFIIH: assignment of functions for the three enzymatic subunits, XPB, XPD, and cdk7 [LiteratureReference:111273] Mechanism of RNA polymerase II--specific initiation of transcription in vitro: ATP requirement and uncapped runoff transcripts.
modified [InstanceEdit:167265] Matthews, L, 2005-10-13 20:53:26 [InstanceEdit:167342] Matthews, L, 2005-10-15 14:03:47 [InstanceEdit:169296] Vastrik, I, 2005-11-28 11:33:22 [InstanceEdit:170174] Gopinathrao, G, 2005-12-25 02:17:30 [InstanceEdit:170793] Vastrik, I, 2006-01-16 05:24:48 [InstanceEdit:2671734] D'Eustachio, P, 2012-11-23 [InstanceEdit:3214351] Gillespie, ME, 2013-03-08 [InstanceEdit:3632906] Gillespie, ME, 2013-05-28 [InstanceEdit:5621512] Matthews, Lisa, 2014-08-29 [InstanceEdit:6787504] D'Eustachio, Peter, 2015-07-13 [InstanceEdit:8946993] Shorser, Solomon, 2016-11-07 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name HIV Promoter Opening: First Transition
output [SimpleEntity:113582] ADP [nucleoplasm] [SimpleEntity:113550] Pi [nucleoplasm] [Complex:167137] HIV-1 open pre-initiation complex [nucleoplasm] [Homo sapiens]
precedingEvent
relatedSpecies [Species:164493] Human immunodeficiency virus 1
releaseDate 2005-09-26
reviewStatus [ReviewStatus:9821382] five stars
species [Species:48887] Homo sapiens
stableIdentifier [StableIdentifier:359250] R-HSA-167097.4
summation [Summation:75950] After assembly of the complete RNA polymerase II-preinitiati...
(hasEvent) [Pathway:167172] Transcription of the HIV genome [Homo sapiens]
(precedingEvent) [Reaction:167118] NTP binds active site of RNA Polymerase II in HIV-1 open pre-initiation complex [Homo sapiens] [Pathway:167161] HIV Transcription Initiation [Homo sapiens] [Reaction:167484] Fall Back to Closed Pre-initiation Complex [Homo sapiens]
(updatedInstance) [_UpdateTracker:9782363] Update Tracker - [Reaction:167097] HIV Promoter Opening: First Transition - v59:[modifyText] [_UpdateTracker:9784244] Update Tracker - [Reaction:167097] HIV Promoter Opening: First Transition - v54:[addLiteratureReference] [_UpdateTracker:9789847] Update Tracker - [Reaction:167097] HIV Promoter Opening: First Transition - v37:[modifyText]
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