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Details on Person DSIF complex binds to RNA Pol II (hypophosphorylated)

Class:IdReaction:167083
_displayNameDSIF complex binds to RNA Pol II (hypophosphorylated)
_doReleaseTRUE
_timestamp2016-11-10 00:55:35
authored[InstanceEdit:165064] Matthews, L, Rice, AP, 2005-07-27 00:00:00
compartment[Compartment:7660] nucleoplasm
created[InstanceEdit:167073] Matthews, L, 2005-10-11 08:25:49
disease[Disease:1660559] Human immunodeficiency virus infectious disease
edited[InstanceEdit:165066] Matthews, L, 2005-07-26 23:29:22
inferredFrom
input[Complex:112420] DSIF complex [nucleoplasm] [Homo sapiens]
[Complex:167086] RNA Pol II (hypophosphorylated):capped pre-mRNA complex [nucleoplasm] [Homo sapiens]
literatureReference[LiteratureReference:113798] DSIF, a novel transcription elongation factor that regulates RNA polymerase II processivity, is composed of human Spt4 and Spt5 homologs.
[LiteratureReference:170767] Domains in the SPT5 protein that modulate its transcriptional regulatory properties
[LiteratureReference:113800] Evidence that P-TEFb alleviates the negative effect of DSIF on RNA polymerase II-dependent transcription in vitro.
[LiteratureReference:113797] Structure-function analysis of human Spt4: evidence that hSpt4 and hSpt5 exert their roles in transcriptional elongation as parts of the DSIF complex.
modified[InstanceEdit:167332] Matthews, L, 2005-10-15 11:57:26
[InstanceEdit:169296] Vastrik, I, 2005-11-28 11:33:22
[InstanceEdit:170174] Gopinathrao, G, 2005-12-25 02:17:30
[InstanceEdit:170768] Matthews, L, 2006-01-15 13:04:15
[InstanceEdit:170793] Vastrik, I, 2006-01-16 05:24:48
[InstanceEdit:2671734] D'Eustachio, P, 2012-11-23
[InstanceEdit:3632906] Gillespie, ME, 2013-05-28
[InstanceEdit:5621512] Matthews, Lisa, 2014-08-29
[InstanceEdit:6787504] D'Eustachio, Peter, 2015-07-13
[InstanceEdit:8946993] Shorser, Solomon, 2016-11-07
[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
nameDSIF complex binds to RNA Pol II (hypophosphorylated)
output[Complex:167070] RNA Pol II (hypophosphorylated) complex bound to DSIF protein [nucleoplasm] [Homo sapiens]
precedingEvent
relatedSpecies[Species:164493] Human immunodeficiency virus 1
releaseDate2005-04-11
reviewStatus[ReviewStatus:9821382] five stars
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:358418] R-HSA-167083.4
summation[Summation:170745] This HIV-1 event was inferred from the corresponding human R...
(hasEvent)[Pathway:167158] Formation of the HIV-1 Early Elongation Complex [Homo sapiens]
(precedingEvent)[Reaction:167085] Formation of DSIF:NELF:HIV-1 early elongation complex [Homo sapiens]
(updatedInstance)[_UpdateTracker:9784274] Update Tracker - [Reaction:167083] DSIF complex binds to RNA Pol II (hypophosphorylated) - v54:[addLiteratureReference]
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