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Details on Person TrkA receptor autophosphorylates

Class:IdReaction:166544
_displayNameTrkA receptor autophosphorylates
_doReleaseTRUE
_timestamp2011-10-24 13:24:22
authored[InstanceEdit:188342] Nasi, Sergio, Annibali, D, 2006-10-10
catalystActivity[CatalystActivity:198204] transmembrane receptor protein tyrosine kinase activity of beta-NGF dimer:TrkA receptor dimer [plasma membrane]
compartment[Compartment:70101] cytosol
[Compartment:876] plasma membrane
created[InstanceEdit:166541] Jassal, Bijay, 2005-09-08
edited[InstanceEdit:188340] Jassal, Bijay, 2006-10-10
inferredFrom
input[Complex:166543] beta-NGF dimer:TrkA receptor dimer [plasma membrane] [Homo sapiens]
[SimpleEntity:113592] ATP [cytosol]
[SimpleEntity:113592] ATP [cytosol]
[SimpleEntity:113592] ATP [cytosol]
[SimpleEntity:113592] ATP [cytosol]
[SimpleEntity:113592] ATP [cytosol]
[SimpleEntity:113592] ATP [cytosol]
[SimpleEntity:113592] ATP [cytosol]
[SimpleEntity:113592] ATP [cytosol]
[SimpleEntity:113592] ATP [cytosol]
[SimpleEntity:113592] ATP [cytosol]
modified[InstanceEdit:166545] Jassal, Bijay, 2005-09-08
[InstanceEdit:167064] 2006-02-07 08:34:19
[InstanceEdit:181805] Jassal, Bijay, 2006-06-20
[InstanceEdit:187730] Jassal, Bijay, 2006-09-21
[InstanceEdit:187903] Jassal, Bijay, 2006-09-29
[InstanceEdit:188324] Jassal, Bijay, 2006-10-06
[InstanceEdit:188328] Jassal, Bijay, 2006-10-06
[InstanceEdit:188337] Jassal, Bijay, 2006-10-10
[InstanceEdit:188431] Gopinathrao, G, 2006-10-12 14:53:00
[InstanceEdit:188624] Jassal, Bijay, 2006-10-19
[InstanceEdit:189699] Jassal, Bijay, 2006-12-01
[InstanceEdit:196906] Gopinathrao, G, 2007-04-25 14:54:44
[InstanceEdit:198207] Jassal, Bijay, 2007-05-21
[InstanceEdit:202683] Jassal, Bijay, 2007-11-08
[InstanceEdit:1043153] Wu, G, 2010-11-19
[InstanceEdit:1806830] Jassal, Bijay, 2011-10-24
[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
nameTrkA receptor autophosphorylates
output[Complex:166540] Activated TrkA receptor complex [plasma membrane] [Homo sapiens]
[SimpleEntity:29370] ADP [cytosol]
[SimpleEntity:29370] ADP [cytosol]
[SimpleEntity:29370] ADP [cytosol]
[SimpleEntity:29370] ADP [cytosol]
[SimpleEntity:29370] ADP [cytosol]
[SimpleEntity:29370] ADP [cytosol]
[SimpleEntity:29370] ADP [cytosol]
[SimpleEntity:29370] ADP [cytosol]
[SimpleEntity:29370] ADP [cytosol]
[SimpleEntity:29370] ADP [cytosol]
precedingEvent
releaseDate2007-12-11
reviewed[InstanceEdit:202668] Greene, LA, 2007-11-08 15:39:37
reviewStatus[ReviewStatus:9821382] five stars
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:360910] R-HSA-166544.2
summation[Summation:167061] NGF binding induces a conformational change in TRKA, which e...
(hasEvent)[Pathway:187042] TRKA activation by NGF [Homo sapiens]
(precedingEvent)[Pathway:167044] Signalling to RAS [Homo sapiens]
[Reaction:167056] SHC binds to the activated TrkA receptor [Homo sapiens]
[Reaction:167674] Binding of PLCG1 to active TrkA receptor [Homo sapiens]
[Reaction:169891] ARMS:Crk complex binds to active TrkA receptor [Homo sapiens]
[Reaction:177491] Formation of clathrin-coated vesicle [Homo sapiens]
[Reaction:187697] TRKA recruits RIT and RIN [Homo sapiens]
[BlackBoxEvent:190065] Activated TrkA receptor internalizes to endosomes [Homo sapiens]
[Reaction:198211] Active TRKA binds IRS1/2 [Homo sapiens]
[Reaction:198732] STAT3 activation [Homo sapiens]
(updatedInstance)[_UpdateTracker:9792262] Update Tracker - [Reaction:166544] TrkA receptor autophosphorylates - v22:[addCatalystActivity, modifyText]
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No pathways have been reviewed or authored by TrkA receptor autophosphorylates (166544)
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