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Details on Person Activated TrkA receptor complex [plasma membrane]
Class:Id Complex:166540
_displayName Activated TrkA receptor complex [plasma membrane]
_timestamp 2013-02-05 13:18:32
compartment [Compartment:876] plasma membrane
created [InstanceEdit:166541] Jassal, Bijay, 2005-09-08
hasComponent
modified [InstanceEdit:166555] Jassal, B, 2005-09-08 12:50:08 [InstanceEdit:167064] 2006-02-07 08:34:19 [InstanceEdit:187008] Jassal, Bijay, 2006-09-07 [InstanceEdit:187902] Jassal, B, 2006-09-29 12:48:21 [InstanceEdit:2018636] Jassal, Bijay, 2011-11-23 [InstanceEdit:2231000] Matthews, L, 2012-05-07 [InstanceEdit:3009414] Jupe, S, 2013-02-05
name Activated TrkA receptor complex
species [Species:48887] Homo sapiens
stableIdentifier [StableIdentifier:368201] R-HSA-166540.1
(activeUnit) [CatalystActivity:167688] transmembrane receptor protein tyrosine kinase activity of Active TrkA receptor:PLCG1 complex [plasma membrane]
(hasComponent) [Complex:167015] Activated TrkA receptor:p-SHC [plasma membrane] [Homo sapiens] [Complex:167020] Activated TrkA receptor:SHC [plasma membrane] [Homo sapiens] [Complex:167681] Active TrkA receptor:Phospho-PLCG1 complex [plasma membrane] [Homo sapiens] [Complex:167687] Active TrkA receptor:PLCG1 complex [plasma membrane] [Homo sapiens] [Complex:169857] Active TrkA receptor:Phospho-ARMS:Crk:C3G complex [plasma membrane] [Homo sapiens] [Complex:169865] Active TrkA receptor:Phospho-ARMS:Crk complex [plasma membrane] [Homo sapiens] [Complex:169871] Active TrkA receptor:ARMS:Crk complex [plasma membrane] [Homo sapiens] [Complex:170967] Active TrkA receptor:Phospho-Frs2:CrkL complex [plasma membrane] [Homo sapiens] [Complex:170969] Active TrkA receptor:Phospho-Frs2:CrkL:C3G:Rap1-GTP complex [plasma membrane] [Homo sapiens] [Complex:170971] Active Trk receptor:Phospho-Frs2:CrkL:C3G:Rap1-GTP:Phospho-B-Raf complex [plasma membrane] [Homo sapiens]
(input) [Reaction:167056] SHC binds to the activated TrkA receptor [Homo sapiens] [Reaction:167674] Binding of PLCG1 to active TrkA receptor [Homo sapiens] [Reaction:169891] ARMS:Crk complex binds to active TrkA receptor [Homo sapiens] [Reaction:177491] Formation of clathrin-coated vesicle [Homo sapiens] [Reaction:187697] TRKA recruits RIT and RIN [Homo sapiens] [BlackBoxEvent:190065] Activated TrkA receptor internalizes to endosomes [Homo sapiens] [Reaction:198211] Active TRKA binds IRS1/2 [Homo sapiens]
(output) [Reaction:166544] TrkA receptor autophosphorylates [Homo sapiens] [Reaction:167217] Phospho-Shc dissociates from the TrkA receptor [Homo sapiens] [Reaction:167684] Active PLCG1 dissociates from TrkA receptor [Homo sapiens]
(physicalEntity) [CatalystActivity:198709] transmembrane receptor protein serine/threonine kinase activity of Activated TrkA receptor complex [plasma membrane]
(updatedInstance) [_UpdateTracker:9871538] Update Tracker - [Complex:166540] Activated TrkA receptor complex [plasma membrane] - v40:[addCompartment] [_UpdateTracker:9872033] Update Tracker - [Complex:166540] Activated TrkA receptor complex [plasma membrane] - v41:[removeCompartment] [_UpdateTracker:9877690] Update Tracker - [Complex:166540] Activated TrkA receptor complex [plasma membrane] - v44:[add_removeHasComponent]
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No pathways have been reviewed or authored by Activated TrkA receptor complex [plasma membrane] (166540)