Reactome: A Curated Pathway Database
THIS SITE IS USED FOR CURATION AND TESTING
IT IS NOT STABLE, IS LINKED TO AN INCOMPLETE DATA SET, AND IS NOT MONITORED FOR PERFORMANCE. WE STRONGLY RECOMMEND THE USE OF OUR PUBLIC SITE

Query author contributions in Reactome

Reactome depends on collaboration between our curation team and outside experts to assemble and peer-review its pathway modules. The integration of ORCID within Reactome enables us to meet a key challenge with authoring, curating and reviewing biological information by incentivizing and crediting the external experts that contribute their expertise and time to the Reactome curation process. More information is available at ORCID and Reactome.

If you have an ORCID ID that is not listed on this page, please forward this information to us and we will update your Reactome pathway records.

Name Email address

Details on Person TBK1 [cytosol]

Class:IdEntityWithAccessionedSequence:166267
_displayNameTBK1 [cytosol]
_timestamp2009-12-16 18:33:15
compartment[Compartment:70101] cytosol
created[InstanceEdit:166266] de Bono, B, 2005-08-23 09:18:08
endCoordinate729
modified[InstanceEdit:450361] Shamovsky, V, 2009-12-16
nameTBK1
referenceEntity[ReferenceGeneProduct:165797] UniProt:Q9UHD2 TBK1 [Homo sapiens]
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:363425] R-HSA-166267.1
startCoordinate1
(hasComponent)[Complex:1834956] STING:TBK1:IRF3 [cytoplasmic vesicle membrane] [Homo sapiens]
[Complex:3249399] STING:TBK1:STAT6 [cytoplasmic vesicle membrane] [Homo sapiens]
[Complex:8983583] IL17RA:IL17RC:IL17A dimer,IL17F dimer,IL17A:IL17F:TRAF3IP2:TRAF6:TBK1 [cytosol] [Homo sapiens]
[Complex:8983585] IL17RA:IL17RC:IL17A dimer,IL17F dimer,IL17A:IL17F:p-S162,S220,S-TRAF3IP2:TRAF6:TBK1 [plasma membrane] [Homo sapiens]
[Complex:9705026] TBK1:pp1ab-nsp6 [double membrane vesicle viral factory outer membrane] [Homo sapiens]
[Complex:9705087] TBK1:pp1ab-nsp13 [cytosol] [Homo sapiens]
[Complex:9709836] HSP90:TBK1:IRF3 [cytosol] [Homo sapiens]
[Complex:9730434] TBK1:TBK1 [cytosol] [Homo sapiens]
[Complex:9754834] M:TBK1 [endoplasmic reticulum-Golgi intermediate compartment membrane] [Homo sapiens]
[Complex:9824896] TBK1:OPTN:K63-polyUb-mitochondrial proteins [cytosol] [Homo sapiens]
List all 11 refering instances
(hasMember)[DefinedSet:450329] TBK1, IKBKE [cytosol] [Homo sapiens]
(input)[Reaction:1606324] Recruitment TBK1 to dsDNA:ZBP1 followed by its activation [Homo sapiens]
[Reaction:1834939] STING recruits TBK1 and IRF3 [Homo sapiens]
[Reaction:3249378] STING recruits TBK1 and STAT6 [Homo sapiens]
[BlackBoxEvent:8983593] TBK1 binds a TRAF3IP2 complex [Homo sapiens]
[BlackBoxEvent:9008684] TBK1 phosphorylation [Homo sapiens]
[Reaction:9705010] SARS-CoV-2 nsp6 binds TBK1 [Homo sapiens]
[Reaction:9705082] SARS-CoV-2 nsp13 binds TBK1 [Homo sapiens]
[Reaction:9709831] HSP90 binds TBK1 and IRF3 [Homo sapiens]
[Reaction:9724203] SOCS3 polyubiquitinates TBK1 [Homo sapiens]
[Reaction:9733871] HHV-1 RL1 binds TBK1 [Homo sapiens]
List all 14 refering instances
(output)[BlackBoxEvent:8983600] TBK1 dissociates from a TRAF3IP2 complex [Homo sapiens]
(physicalEntity)[CatalystActivity:9687850] protein serine/threonine kinase activity of TBK1 [cytosol]
(updatedInstance)[_UpdateTracker:9868827] Update Tracker - [EntityWithAccessionedSequence:166267] TBK1 [cytosol] - v32:[addEndCoordinate, addStartCoordinate]
[Change default viewing format]
No pathways have been reviewed or authored by TBK1 [cytosol] (166267)