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Details on Person TRAM:TLR4:LY96:LPS:CD14 recruits TRIF (TICAM1)

Class:Id	Reaction:166175
_displayName	TRAM:TLR4:LY96:LPS:CD14 recruits TRIF (TICAM1)
_doRelease	TRUE
_timestamp	2016-06-22 20:53:47
authored	[InstanceEdit:166017] de Bono, B, 2005-08-16 10:54:15
compartment	[Compartment:74700] endosome membrane [Compartment:70101] cytosol
created	[InstanceEdit:166176] de Bono, B, 2005-08-19 15:48:42
edited	[InstanceEdit:1485578] Shamovsky, V, 2011-08-12
input	[EntityWithAccessionedSequence:166170] TICAM1 [cytosol] [Homo sapiens] [Complex:166163] TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] [Homo sapiens] [EntityWithAccessionedSequence:166170] TICAM1 [cytosol] [Homo sapiens]
literatureReference	[LiteratureReference:177881] Role of adaptor TRIF in the MyD88-independent toll-like receptor signaling pathway [LiteratureReference:165861] TRAM is specifically involved in the Toll-like receptor 4-mediated [LiteratureReference:165909] LPS-TLR4 signaling to IRF-3/7 and NF-kappaB involves the toll adapters
modified	[InstanceEdit:166841] de Bono, B, 2005-09-19 11:41:25 [InstanceEdit:168952] de Bono, B, 2005-11-22 18:52:15 [InstanceEdit:169811] de Bono, B, 2005-12-07 10:56:20 [InstanceEdit:177473] Gopinathrao, G, 2006-03-30 18:00:11 [InstanceEdit:177514] Gopinathrao, G, 2006-03-31 14:29:10 [InstanceEdit:188666] de Bono, B, 2006-10-20 12:06:04 [InstanceEdit:188944] Gopinathrao, G, 2006-10-31 10:11:13 [InstanceEdit:188963] Gopinathrao, G, 2006-11-01 22:14:37 [InstanceEdit:937088] Shamovsky, V, 2010-08-25 [InstanceEdit:1018389] Shamovsky, V, 2010-11-16 [InstanceEdit:1080813] D'Eustachio, P, 2010-11-27 [InstanceEdit:1095193] Shamovsky, V, 2010-11-30 [InstanceEdit:1551958] Shamovsky, V, 2011-08-30 [InstanceEdit:1602499] Shamovsky, V, 2011-09-14 [InstanceEdit:2201357] Shamovsky, V, 2012-04-19 [InstanceEdit:2248861] Shamovsky, V, 2012-05-15 [InstanceEdit:2582979] Shamovsky, V, 2012-11-13 [InstanceEdit:2632486] Shamovsky, V, 2012-11-20 [InstanceEdit:2632490] Shamovsky, V, 2012-11-20 [InstanceEdit:3621903] Shamovsky, V, 2013-05-24 [InstanceEdit:5676057] Shamovsky, Veronica, 2015-02-18 [InstanceEdit:8877183] Orlic-Milacic, Marija, 2016-06-21 [InstanceEdit:8877506] Orlic-Milacic, Marija, 2016-06-22 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	TRAM:TLR4:LY96:LPS:CD14 recruits TRIF (TICAM1)
output	[Complex:166172] TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] [Homo sapiens]
releaseDate	2010-12-14
reviewed	[InstanceEdit:188961] Gay, NJ, 2006-04-24 16:48:17 [InstanceEdit:1095192] Gillespie, ME, 2010-11-30 [InstanceEdit:2582977] Fitzgerald, Katherine A, 2012-11-13
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:361230] R-HSA-166175.3
summation	[Summation:169810] TRIF (TICAM1) mediates the MyD88-independent pathway from TL...
(hasEvent)	[Pathway:166166] MyD88-independent TLR4 cascade [Homo sapiens]
(precedingEvent)	[Reaction:168921] TRIF:activated TLR3/TLR4 complex recruits RIP1 [Homo sapiens] [Reaction:936985] Activated TLR4:TICAM1 recruits TRAF6 [Homo sapiens] [Reaction:2201338] TRAF3 binds TICAM1:activated TLR4 complex [Homo sapiens] [Reaction:2559568] SARM binds TICAM1:TRAM:TLR4:LY96:LPS:CD14 [Homo sapiens]
(updatedInstance)	[_UpdateTracker:9782882] Update Tracker - [Reaction:166175] TRAM:TLR4:LY96:LPS:CD14 recruits TRIF (TICAM1) - v58:[modifyText] [_UpdateTracker:9787395] Update Tracker - [Reaction:166175] TRAM:TLR4:LY96:LPS:CD14 recruits TRIF (TICAM1) - v45:[modifyText] [_UpdateTracker:9788592] Update Tracker - [Reaction:166175] TRAM:TLR4:LY96:LPS:CD14 recruits TRIF (TICAM1) - v41:[addLiteratureReference]
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No pathways have been reviewed or authored by TRAM:TLR4:LY96:LPS:CD14 recruits TRIF (TICAM1) (166175)