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Details on Person IRAK1/or IRAK2:p-IRAK4:MyD88 oligomer:TIRAP:activated TLR [plasma membrane]

Class:IdComplex:166100
_displayNameIRAK1/or IRAK2:p-IRAK4:MyD88 oligomer:TIRAP:activated TLR [plasma membrane]
_timestamp2018-08-09 02:30:00
compartment[Compartment:876] plasma membrane
created[InstanceEdit:166099] de Bono, B, 2005-08-17 10:44:00
hasComponent
literatureReference[LiteratureReference:937049] Helical assembly in the MyD88-IRAK4-IRAK2 complex in TLR/IL-1R signalling
[LiteratureReference:571295] Identification of critical residues of the MyD88 death domain involved in the recruitment of downstream kinases
[LiteratureReference:2428888] Mal (MyD88-adapter-like) is required for Toll-like receptor-4 signal transduction
[LiteratureReference:2428820] IRAK1 and IRAK4 promote phosphorylation, ubiquitination, and degradation of MyD88 adaptor-like (Mal)
modified[InstanceEdit:166112] de Bono, B, 2005-08-18 13:46:23
[InstanceEdit:181367] de Bono, B, 2006-06-09 09:29:19
[InstanceEdit:937095] Shamovsky, V, 2010-08-25
[InstanceEdit:1013005] Shamovsky, V, 2010-11-11
[InstanceEdit:1564950] Shamovsky, V, 2011-09-06
[InstanceEdit:2428905] Shamovsky, V, 2012-08-08
[InstanceEdit:8959586] Weiser, JD
[InstanceEdit:9615894] Shamovsky, Veronica, 2018-08-09
nameIRAK1/or IRAK2:p-IRAK4:MyD88 oligomer:TIRAP:activated TLR
IRAK1/or IRAK2:p-IRAK4:MyD88 oligomer:Mal:activated TLR
relatedSpecies[Species:181384] Chlamydia trachomatis
[Species:180800] Neisseria meningitidis serogroup B
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:366976] R-HSA-166100.3
(inferredFrom)[Complex:434002] IRAK2 : p-IRAK4 :MyD88 : TIRAP : activated TLR [plasma membrane] [Gallus gallus]
[Complex:977244] IRAK2 : p-IRAK4 :MyD88 : activated TLR [plasma membrane] [Gallus gallus]
(output)[Reaction:166091] IRAK1 or IRAK2 binds to the activated IRAK4 :activated TLR:MyD88:TIRAP complex [Homo sapiens]
(updatedInstance)[_UpdateTracker:9863788] Update Tracker - [Complex:166100] IRAK1/or IRAK2:p-IRAK4:MyD88 oligomer:TIRAP:activated TLR [plasma membrane] - v20:[updateContainedComponent]
[_UpdateTracker:9867519] Update Tracker - [Complex:166100] IRAK1/or IRAK2:p-IRAK4:MyD88 oligomer:TIRAP:activated TLR [plasma membrane] - v25:[updateContainedComponent]
[_UpdateTracker:9868462] Update Tracker - [Complex:166100] IRAK1/or IRAK2:p-IRAK4:MyD88 oligomer:TIRAP:activated TLR [plasma membrane] - v31:[updateContainedComponent]
[_UpdateTracker:9868745] Update Tracker - [Complex:166100] IRAK1/or IRAK2:p-IRAK4:MyD88 oligomer:TIRAP:activated TLR [plasma membrane] - v32:[updateContainedComponent]
[_UpdateTracker:9870223] Update Tracker - [Complex:166100] IRAK1/or IRAK2:p-IRAK4:MyD88 oligomer:TIRAP:activated TLR [plasma membrane] - v38:[updateContainedComponent]
[_UpdateTracker:9870983] Update Tracker - [Complex:166100] IRAK1/or IRAK2:p-IRAK4:MyD88 oligomer:TIRAP:activated TLR [plasma membrane] - v39:[updateContainedComponent]
[_UpdateTracker:9872001] Update Tracker - [Complex:166100] IRAK1/or IRAK2:p-IRAK4:MyD88 oligomer:TIRAP:activated TLR [plasma membrane] - v41:[updateContainedComponent]
[_UpdateTracker:9873203] Update Tracker - [Complex:166100] IRAK1/or IRAK2:p-IRAK4:MyD88 oligomer:TIRAP:activated TLR [plasma membrane] - v42:[addLiteratureReference, updateContainedComponent]
[_UpdateTracker:9874058] Update Tracker - [Complex:166100] IRAK1/or IRAK2:p-IRAK4:MyD88 oligomer:TIRAP:activated TLR [plasma membrane] - v43:[updateContainedComponent]
[_UpdateTracker:9889381] Update Tracker - [Complex:166100] IRAK1/or IRAK2:p-IRAK4:MyD88 oligomer:TIRAP:activated TLR [plasma membrane] - v49:[updateContainedComponent]
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No pathways have been reviewed or authored by IRAK1/or IRAK2:p-IRAK4:MyD88 oligomer:TIRAP:activated TLR [plasma membrane] (166100)
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