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Details on Person Pitha-Rowe, Paula M

Class:Id	Person:165908
_displayName	Pitha-Rowe, Paula M
_timestamp	2016-07-20 19:18:07
affiliation	[Affiliation:157517] Johns Hopkins University
created	[InstanceEdit:165911] de Bono, B, 2005-08-11 15:33:55
firstname	Paula M
initial	PM
modified	[InstanceEdit:1237406] D'Eustachio, P, 2011-03-30 [InstanceEdit:8932050] D'Eustachio, Peter, 2016-07-20
surname	Pitha-Rowe
(author)	[LiteratureReference:165909] LPS-TLR4 signaling to IRF-3/7 and NF-kappaB involves the toll adapters [LiteratureReference:166253] Virus-dependent phosphorylation of the IRF-3 transcription factor regulates nuclear translocation, transactivation potential, and proteasome-mediated degradation [LiteratureReference:975484] The interferon regulatory factor, IRF5, is a central mediator of toll-like receptor 7 signaling [LiteratureReference:1169306] Innate antiviral response targets HIV-1 release by the induction of ubiquitin-like protein ISG15 [LiteratureReference:1169331] ISG15 inhibits Ebola VP40 VLP budding in an L-domain-dependent manner by blocking Nedd4 ligase activity [LiteratureReference:1169352] ISG15 enhances the innate antiviral response by inhibition of IRF-3 degradation
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No pathways have been reviewed or authored by Pitha-Rowe, Paula M (165908)