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Details on Person Expression of ELOVL6

Class:Id	BlackBoxEvent:1655835
_displayName	Expression of ELOVL6
_doRelease	TRUE
_timestamp	2026-04-13 17:17:25
authored	[InstanceEdit:1655770] May, B, 2011-09-28
compartment	[Compartment:7660] nucleoplasm [Compartment:12045] endoplasmic reticulum membrane
created	[InstanceEdit:1655841] May, B, 2011-10-13
edited	[InstanceEdit:1655770] May, B, 2011-09-28
goBiologicalProcess	[GO_BiologicalProcess:258336] gene expression
input	[EntityWithAccessionedSequence:2393996] ELOVL6 gene [nucleoplasm] [Homo sapiens]
isChimeric	FALSE
literatureReference	[LiteratureReference:1660633] ELOVL1 production of C24 acyl-CoAs is linked to C24 sphingolipid synthesis
modified	[InstanceEdit:1660648] May, B, 2011-10-14 [InstanceEdit:2394002] May, B, 2012-06-28 [InstanceEdit:2426205] May, B, 2012-07-29 [InstanceEdit:2426206] May, B, 2012-07-30 [InstanceEdit:2426449] May, B, 2012-08-03 [InstanceEdit:2426556] May, B, 2012-08-04 [InstanceEdit:2426692] May, B, 2012-08-08 [InstanceEdit:2457633] May, B, 2012-08-25 [InstanceEdit:8963807] May, Bruce, 2017-02-13 [InstanceEdit:9606200] Wu, G, 2018-04-19 [InstanceEdit:9626991] May, Bruce, 2018-10-31 [InstanceEdit:9641190] Wu, G, 2019-04-04 [InstanceEdit:9733355] Wu, Guanming, 2021-06-04 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08 [InstanceEdit:9961220] D'Eustachio, Peter, 2025-07-21 [InstanceEdit:9987322] D'Eustachio, Peter, 2026-04-13
name	Expression of ELOVL6
output	[EntityWithAccessionedSequence:548680] ELOVL6 [endoplasmic reticulum membrane] [Homo sapiens]
precedingEvent	[Reaction:2426149] SREBP1A,1C,2 binds the ELOVL6 promoter [Homo sapiens] [Reaction:2065539] SREBP1A,1C,2:Importin beta-1 dissociates [Homo sapiens]
regulatedBy	[PositiveGeneExpressionRegulation:1655862] Positive gene expression regulation by 'SREBP1A,1C,2:ELOVL6 gene [nucleoplasm]'
regulationReference	[RegulationReference:9642050] Positive gene expression regulation by 'SREBP1A,1C,2:ELOVL6 gene [nucleoplasm]' Mouse Elovl-6 promoter is an SREBP target
releaseDate	2012-09-18
reviewed	[InstanceEdit:2457630] Liang, Guosheng, 2012-08-25
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:2465020] R-HSA-1655835.8
summation	[Summation:1655808] The ELOVL6 gene is transcribed to yield mRNA and the mRNA is... [Summation:1655804] As inferred from mouse, SREBF1A/1C/2 (SREBP1A/1C/2) bind the...
(hasEvent)	[Pathway:2426168] Activation of gene expression by SREBF (SREBP) [Homo sapiens]
(updatedInstance)	[_UpdateTracker:9776065] Update Tracker - [BlackBoxEvent:1655835] Expression of ELOVL6 - v78:[addSummation] [_UpdateTracker:9781947] Update Tracker - [BlackBoxEvent:1655835] Expression of ELOVL6 - v60:[add_removeInput]
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No pathways have been reviewed or authored by Expression of ELOVL6 (1655835)