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Details on Person Rev multimer-bound HIV mRNA:Crm1:Ran:GTP complex associates with the NPC

Class:Id	Reaction:165043
_displayName	Rev multimer-bound HIV mRNA:Crm1:Ran:GTP complex associates with the NPC
_doRelease	TRUE
_timestamp	2016-11-10 00:55:25
authored	[InstanceEdit:165064] Matthews, L, Rice, AP, 2005-07-27 00:00:00
compartment	[Compartment:7660] nucleoplasm [Compartment:13231] nuclear envelope
created	[InstanceEdit:165042] Matthews, L, 2005-07-26 23:04:06
disease	[Disease:1660559] Human immunodeficiency virus infectious disease
edited	[InstanceEdit:182779] Matthews, L, 2006-07-13 06:31:19
input	[Complex:157689] Nuclear Pore Complex (NPC) [nuclear envelope] [Homo sapiens] [Complex:165537] Rev multimer-bound HIV-1 mRNA:Crm1:Ran:GTP [nucleoplasm] [Homo sapiens]
literatureReference	[LiteratureReference:6787490] Structural basis for cooperative RNA binding and export complex assembly by HIV Rev [LiteratureReference:167644] The specificity of the CRM1-Rev nuclear export signal interaction is mediated by RanGTP
modified	[InstanceEdit:165534] Matthews, L, 2005-08-03 12:39:20 [InstanceEdit:165610] Matthews, L, 2005-08-08 05:19:16 [InstanceEdit:167666] Matthews, L, 2005-11-01 06:14:27 [InstanceEdit:169296] Vastrik, I, 2005-11-28 11:33:22 [InstanceEdit:170174] Gopinathrao, G, 2005-12-25 02:17:30 [InstanceEdit:170276] Matthews, L, 2006-01-05 00:32:35 [InstanceEdit:170276] Matthews, L, 2006-01-05 00:32:35 [InstanceEdit:170421] Matthews, L, 2006-01-06 00:16:54 [InstanceEdit:180927] Matthews, L, 2006-06-07 20:09:40 [InstanceEdit:192381] Matthews, L, 2007-01-31 23:58:33 [InstanceEdit:1043153] Wu, G, 2010-11-19 [InstanceEdit:3214351] Gillespie, ME, 2013-03-08 [InstanceEdit:3632906] Gillespie, ME, 2013-05-28 [InstanceEdit:5621512] Matthews, Lisa, 2014-08-29 [InstanceEdit:6787489] D'Eustachio, Peter, 2015-07-13 [InstanceEdit:8946993] Shorser, Solomon, 2016-11-07 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	Rev multimer-bound HIV mRNA:Crm1:Ran:GTP complex associates with the NPC
output	[Complex:165531] Rev multimer-bound HIV-1 mRNA:Crm1:Ran:GTP:NPC [nuclear envelope] [Homo sapiens]
precedingEvent	[Reaction:165034] Rev multimer-bound HIV mRNA:CRM1 complex associates with Ran:GTP [Homo sapiens] [Reaction:165033] Multimerization of Rev [Homo sapiens] [Reaction:180687] Conversion of Ran-GDP to Ran-GTP [Homo sapiens]
relatedSpecies	[Species:164493] Human immunodeficiency virus 1
releaseDate	2005-06-13
reviewed	[InstanceEdit:192365] Kumar, A, 2007-01-31 22:47:49
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:361672] R-HSA-165043.4
summation	[Summation:179157] The Rev multimer-bound HIV-1 mRNA:Crm1:Ran:GTP complex assoc...
(hasEvent)	[Pathway:165054] Rev-mediated nuclear export of HIV RNA [Homo sapiens]
(precedingEvent)	[Reaction:165047] Translocation of nuclear RNA transport complex to cytoplasm [Homo sapiens]
(updatedInstance)	[_UpdateTracker:9784360] Update Tracker - [Reaction:165043] Rev multimer-bound HIV mRNA:Crm1:Ran:GTP complex associates with the NPC - v54:[addLiteratureReference, modifyText]
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No pathways have been reviewed or authored by Rev multimer-bound HIV mRNA:Crm1:Ran:GTP complex associates with the NPC (165043)