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Details on Person Crm1 is a nucleocytoplasmic transport factor that is believe...

Class:Id	Summation:165029
_displayName	Crm1 is a nucleocytoplasmic transport factor that is believe...
_timestamp	2005-11-08 00:59:13
created	[InstanceEdit:165042] Matthews, L, 2005-07-26 23:04:06
literatureReference	[LiteratureReference:165620] Retroviruses as model systems for the study of nuclear RNA export [LiteratureReference:165040] CRM1 is an export receptor for leucine-rich nuclear export signals [LiteratureReference:167658] The human homologue of yeast CRM1 is in a dynamic subcomplex with CAN/Nup214 and a novel nuclear pore component Nup88
modified	[InstanceEdit:167654] Matthews, L, 2005-11-01 06:13:21 [InstanceEdit:167733] Matthews, L, 2005-11-08 00:59:08
text	Crm1 is a nucleocytoplasmic transport factor that is believed to interact with nucleoporins facilitating docking of the RRE-Rev-CRM1-RanGTP complex to the nuclear pore and the translocation of the complex across the nuclear pore complex (see Cullen 1998) Crm1 has been found in complex with two such nucleoporins, CAN/Nup214 and Nup88 which have been shown to be components of the human nuclear pore complex (Fornerod et al., 1997).
(summation)	[Reaction:165047] Translocation of nuclear RNA transport complex to cytoplasm [Homo sapiens]
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