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Details on Person Transesterification to connect viral DNA 3' ends to host DNA 5' ends

Class:Id	Reaction:164523
_displayName	Transesterification to connect viral DNA 3' ends to host DNA 5' ends
_doRelease	TRUE
_timestamp	2016-11-10 00:56:59
authored	[InstanceEdit:180401] Gopinathrao, G, D'Eustachio, P, 2006-05-18 20:10:22
catalystActivity	[CatalystActivity:175070] integrase activity of IN:viral DNA bound to host genomic DNA with staggered ends [nucleoplasm]
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:164501] D'Eustachio, P, 2005-05-24 15:07:45
disease	[Disease:1660559] Human immunodeficiency virus infectious disease
edited	[InstanceEdit:180401] Gopinathrao, G, D'Eustachio, P, 2006-05-18 20:10:22
figure	[Figure:176001] /figures/strand1x.jpg
input	[Complex:175224] IN:viral DNA bound to host genomic DNA with staggered ends [nucleoplasm] [Homo sapiens]
literatureReference	[Book:175927] 9780879695712 Integration Retroviruses Coffin, JM [LiteratureReference:175622] HIV cDNA integration: molecular biology and inhibitor development [Book:175907] 9781461559252 Retroviral cDNA integration: mechanism, applications and inhibition Genetic Engineering: Principles and Methods Setlow, Jane K
modified	[InstanceEdit:170174] Gopinathrao, G, 2005-12-25 02:17:30 [InstanceEdit:170617] Gopinathrao, G, 2006-01-08 02:23:40 [InstanceEdit:174501] Gopinathrao, G, 2006-02-17 21:37:08 [InstanceEdit:175576] Gopinathrao, G, 2006-02-23 23:50:37 [InstanceEdit:175638] Gopinathrao, G, 2006-02-25 14:03:09 [InstanceEdit:175936] Gopinathrao, G, 2006-02-25 14:09:53 [InstanceEdit:176000] Gopinathrao, G, 2006-02-27 15:06:24 [InstanceEdit:177399] Gopinathrao, G, 2006-03-29 16:14:14 [InstanceEdit:177473] Gopinathrao, G, 2006-03-30 18:00:11 [InstanceEdit:177549] Gopinathrao, G, 2006-04-02 12:03:28 [InstanceEdit:180083] Gopinathrao, G, 2006-05-16 19:02:00 [InstanceEdit:180402] Gopinathrao, G, 2006-05-18 20:43:08 [InstanceEdit:182890] Gopinathrao, G, 2006-07-20 19:02:21 [InstanceEdit:188431] Gopinathrao, G, 2006-10-12 14:53:00 [InstanceEdit:188941] Gopinathrao, G, 2006-10-30 22:24:14 [InstanceEdit:3632906] Gillespie, ME, 2013-05-28 [InstanceEdit:5621512] Matthews, Lisa, 2014-08-29 [InstanceEdit:8855598] D'Eustachio, Peter, 2016-02-04 [InstanceEdit:8855622] D'Eustachio, Peter, 2016-02-04 [InstanceEdit:8946993] Shorser, Solomon, 2016-11-07 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	Transesterification to connect viral DNA 3' ends to host DNA 5' ends
output	[Complex:175148] Integration intermediate [nucleoplasm] [Homo sapiens]
precedingEvent	[Reaction:175108] Target DNA binding [Homo sapiens] [Reaction:162590] Import of PIC to the Host Nucleus [Homo sapiens]
relatedSpecies	[Species:164493] Human immunodeficiency virus 1
releaseDate	2006-11-16
reviewed	[InstanceEdit:188934] Bushman, FD, 2006-10-30 22:19:13
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:360307] R-HSA-164523.4
summation	[Summation:180180] The first chemical step of integration involves a single ste...
(hasEvent)	[Pathway:175567] Integration of viral DNA into host genomic DNA [Homo sapiens]
(precedingEvent)	[Reaction:164506] Gap repair completes provirus integration [Homo sapiens]
(updatedInstance)	[_UpdateTracker:9783707] Update Tracker - [Reaction:164523] Transesterification to connect viral DNA 3' ends to host DNA 5' ends - v56:[removeInput, removeOutput]
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No pathways have been reviewed or authored by Transesterification to connect viral DNA 3' ends to host DNA 5' ends (164523)