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Details on Person Insertion of gp41 fusion peptide into the target membrane
Class:Id Reaction:164521
_displayName Insertion of gp41 fusion peptide into the target membrane
_doRelease TRUE
_timestamp 2016-11-10 00:56:43
authored [InstanceEdit:176401] Morrow, MP, Bukrinsky, Michael, 2006-03-07
compartment [Compartment:876] plasma membrane
created [InstanceEdit:164501] D'Eustachio, P, 2005-05-24 15:07:45
disease [Disease:1660559] Human immunodeficiency virus infectious disease
edited [InstanceEdit:174499] Gopinathrao, G, 2006-02-17 18:35:46
input [Complex:173639] Virion with fusogenically activated gp41 [extracellular region] [Homo sapiens]
literatureReference [LiteratureReference:175780] Effects of amino acid changes in the extracellular domain of the human immunodeficiency virus type 1 gp41 envelope glycoprotein [LiteratureReference:175738] Characterization of the fusion domain of the human immunodeficiency virus type 1 envelope glycoprotein gp41 [LiteratureReference:175692] Inhibition of HIV-1 infection by a fusion domain binding peptide from the HIV-1 envelope glycoprotein GP41 [LiteratureReference:175855] A synthetic peptide inhibitor of human immunodeficiency virus replication: correlation between solution structure and viral inhibition
modified [InstanceEdit:170174] Gopinathrao, G, 2005-12-25 02:17:30 [InstanceEdit:170617] Gopinathrao, G, 2006-01-08 02:23:40 [InstanceEdit:171300] Gopinathrao, G, 2006-02-02 22:47:08 [InstanceEdit:173116] Gopinathrao, G, 2006-02-07 19:48:25 [InstanceEdit:173655] Gopinathrao, G, 2006-02-15 22:15:48 [InstanceEdit:174501] Gopinathrao, G, 2006-02-17 21:37:08 [InstanceEdit:175576] Gopinathrao, G, 2006-02-23 23:50:37 [InstanceEdit:175638] Gopinathrao, G, 2006-02-25 14:03:09 [InstanceEdit:176000] Gopinathrao, G, 2006-02-27 15:06:24 [InstanceEdit:176080] Gopinathrao, G, 2006-03-02 15:50:19 [InstanceEdit:176402] Gopinathrao, G, 2006-03-07 21:34:46 [InstanceEdit:177399] Gopinathrao, G, 2006-03-29 16:14:14 [InstanceEdit:177564] Gopinathrao, G, 2006-04-03 16:21:29 [InstanceEdit:177633] Gopinathrao, G, 2006-04-03 16:46:21 [InstanceEdit:178122] Gopinathrao, G, 2006-04-17 19:55:39 [InstanceEdit:180083] Gopinathrao, G, 2006-05-16 19:02:00 [InstanceEdit:180650] Gopinathrao, G, 2006-05-30 19:47:43 [InstanceEdit:181877] Gopinathrao, G, 2006-06-26 15:27:09 [InstanceEdit:182677] Gopinathrao, G, 2006-07-12 03:00:19 [InstanceEdit:2984231] Gillespie, ME, 2013-01-15 [InstanceEdit:3632906] Gillespie, ME, 2013-05-28 [InstanceEdit:5621512] Matthews, Lisa, 2014-08-29 [InstanceEdit:8946993] Shorser, Solomon, 2016-11-07 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name Insertion of gp41 fusion peptide into the target membrane
output [Complex:173656] Virion with gp41 fusion peptide in insertion complex [extracellular region] [Homo sapiens]
precedingEvent
relatedSpecies [Species:164493] Human immunodeficiency virus 1
releaseDate 2006-08-02
reviewed [InstanceEdit:181880] Reeves, J, 2006-06-12 15:22:40
reviewStatus [ReviewStatus:9821382] five stars
species [Species:48887] Homo sapiens
stableIdentifier [StableIdentifier:358784] R-HSA-164521.3
summation [Summation:177616] Insertion of the N-terminal fusion peptide of the HIV gp41 p...
(hasEvent) [Pathway:164502] Transition of gp41 to its fusogenic conformation [Homo sapiens] [Pathway:173107] Binding and entry of HIV virion [Homo sapiens]
(precedingEvent) [Reaction:164508] N and C terminal heptad repeat helices of gp41 form six-helix bundle [Homo sapiens]
(updatedInstance) [_UpdateTracker:9782423] Update Tracker - [Reaction:164521] Insertion of gp41 fusion peptide into the target membrane - v59:[modifyText] [_UpdateTracker:9789845] Update Tracker - [Reaction:164521] Insertion of gp41 fusion peptide into the target membrane - v37:[modifyText]
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