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Details on Person Conformational changes in gp120 exposes gp41
Class:Id Reaction:164500
_displayName Conformational changes in gp120 exposes gp41
_doRelease TRUE
_timestamp 2016-11-10 00:54:52
authored [InstanceEdit:176401] Morrow, MP, Bukrinsky, Michael, 2006-03-07
compartment [Compartment:876] plasma membrane
created [InstanceEdit:164501] D'Eustachio, P, 2005-05-24 15:07:45
disease [Disease:1660559] Human immunodeficiency virus infectious disease
edited [InstanceEdit:174499] Gopinathrao, G, 2006-02-17 18:35:46
input [Complex:173663] Virion with CD4:gp120 bound to CCR5/CXCR4 [extracellular region] [Homo sapiens]
literatureReference [LiteratureReference:175636] The ectodomain of HIV-1 env subunit gp41 forms a soluble, alpha-helical, rod-like oligomer in the absence of gp120 and the N-terminal fusion peptide [LiteratureReference:175777] A spring-loaded mechanism for the conformational change of influenza hemagglutinin [LiteratureReference:175804] Functional regions of the envelope glycoprotein of human immunodeficiency virus type 1 [LiteratureReference:177620] Identification of the fusion peptide of primate immunodeficiency viruses
modified [InstanceEdit:170174] Gopinathrao, G, 2005-12-25 02:17:30 [InstanceEdit:170617] Gopinathrao, G, 2006-01-08 02:23:40 [InstanceEdit:171300] Gopinathrao, G, 2006-02-02 22:47:08 [InstanceEdit:173116] Gopinathrao, G, 2006-02-07 19:48:25 [InstanceEdit:173655] Gopinathrao, G, 2006-02-15 22:15:48 [InstanceEdit:174501] Gopinathrao, G, 2006-02-17 21:37:08 [InstanceEdit:175576] Gopinathrao, G, 2006-02-23 23:50:37 [InstanceEdit:175638] Gopinathrao, G, 2006-02-25 14:03:09 [InstanceEdit:176000] Gopinathrao, G, 2006-02-27 15:06:24 [InstanceEdit:176080] Gopinathrao, G, 2006-03-02 15:50:19 [InstanceEdit:176402] Gopinathrao, G, 2006-03-07 21:34:46 [InstanceEdit:177399] Gopinathrao, G, 2006-03-29 16:14:14 [InstanceEdit:177564] Gopinathrao, G, 2006-04-03 16:21:29 [InstanceEdit:177633] Gopinathrao, G, 2006-04-03 16:46:21 [InstanceEdit:178122] Gopinathrao, G, 2006-04-17 19:55:39 [InstanceEdit:180083] Gopinathrao, G, 2006-05-16 19:02:00 [InstanceEdit:180361] Gopinathrao, G, 2006-05-18 15:01:26 [InstanceEdit:180650] Gopinathrao, G, 2006-05-30 19:47:43 [InstanceEdit:181877] Gopinathrao, G, 2006-06-26 15:27:09 [InstanceEdit:182677] Gopinathrao, G, 2006-07-12 03:00:19 [InstanceEdit:2984231] Gillespie, ME, 2013-01-15 [InstanceEdit:3632906] Gillespie, ME, 2013-05-28 [InstanceEdit:5621512] Matthews, Lisa, 2014-08-29 [InstanceEdit:8946993] Shorser, Solomon, 2016-11-07 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name Conformational changes in gp120 exposes gp41
output [Complex:173665] Virion with gp41 exposed [extracellular region] [Homo sapiens]
precedingEvent
relatedSpecies [Species:164493] Human immunodeficiency virus 1
releaseDate 2006-08-02
reviewed [InstanceEdit:181880] Reeves, J, 2006-06-12 15:22:40
reviewStatus [ReviewStatus:9821382] five stars
species [Species:48887] Homo sapiens
stableIdentifier [StableIdentifier:360890] R-HSA-164500.3
summation [Summation:177623] The HIV protein known as gp41 is a transmembrane protein whi...
(hasEvent) [Pathway:173107] Binding and entry of HIV virion [Homo sapiens]
(precedingEvent) [Reaction:164515] Fusogenic activation of gp41 [Homo sapiens]
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