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Details on Person ChREBP (Carbohydrate Response Element Binding Protein) doubl...

Class:IdSummation:164425
_displayNameChREBP (Carbohydrate Response Element Binding Protein) doubl...
_timestamp2022-12-23 22:02:03
created[InstanceEdit:164424] Gopinathrao, G, 2005-05-19 19:11:43
literatureReference[LiteratureReference:8984686] Regulation of nuclear import/export of carbohydrate response element-binding protein (ChREBP): interaction of an alpha-helix of ChREBP with the 14-3-3 proteins and regulation by phosphorylation
modified[InstanceEdit:164567] D'Eustachio, P, 2005-05-26 21:10:03
[InstanceEdit:165156] Gopinathrao, G, 2005-07-29 21:00:28
[InstanceEdit:8984615] Duenas, Corina, 2017-04-10
[InstanceEdit:9822441] D'Eustachio, Peter, 2022-12-23
textChREBP (Carbohydrate Response Element Binding Protein) doubly phosphorylated at threonine 653 and serine 196 is inactive and is localized to the cytosol. Removal of the phosphate residue at serine 196 allows ChREBP to translocate between the cytosol and the nucleoplasm (Sakiyama et al. 2008).
(summation)[BlackBoxEvent:163670] Nuclear transport of pChREBP (Thr 666) protein [Homo sapiens]
[BlackBoxEvent:164423] PhosphoChREBP (Thr 653) is exported to cytosol [Homo sapiens]
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