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Details on Person PhosphoChREBP (Thr 653) is exported to cytosol

Class:Id	BlackBoxEvent:164423
_displayName	PhosphoChREBP (Thr 653) is exported to cytosol
_doRelease	TRUE
_timestamp	2025-07-18 14:55:32
authored	[InstanceEdit:164424] Gopinathrao, G, 2005-05-19 19:11:43
compartment	[Compartment:70101] cytosol [Compartment:7660] nucleoplasm
created	[InstanceEdit:164424] Gopinathrao, G, 2005-05-19 19:11:43
goBiologicalProcess	[GO_BiologicalProcess:160102] nuclear export
input	[EntityWithAccessionedSequence:164349] p-T653-MLXIPL [nucleoplasm] [Homo sapiens]
literatureReference	[LiteratureReference:8984686] Regulation of nuclear import/export of carbohydrate response element-binding protein (ChREBP): interaction of an alpha-helix of ChREBP with the 14-3-3 proteins and regulation by phosphorylation
modified	[InstanceEdit:165156] Gopinathrao, G, 2005-07-29 21:00:28 [InstanceEdit:166004] Gopinathrao, G, 2005-08-12 11:14:59 [InstanceEdit:2671770] D'Eustachio, P, 2012-11-25 [InstanceEdit:8946993] Shorser, Solomon, 2016-11-07 [InstanceEdit:8984615] Duenas, Corina, 2017-04-10 [InstanceEdit:9822441] D'Eustachio, Peter, 2022-12-23 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08 [InstanceEdit:9857755] D'Eustachio, Peter, 2024-01-08 [InstanceEdit:9961000] D'Eustachio, Peter, 2025-07-18
name	PhosphoChREBP (Thr 653) is exported to cytosol
output	[EntityWithAccessionedSequence:164365] p-T653-MLXIPL [cytosol] [Homo sapiens]
precedingEvent	[Reaction:163672] Phosphorylation of ChREBP at Thr(653) by PKA [Homo sapiens] [Reaction:111924] PKA catalytic subunit translocates to the nucleus [Homo sapiens]
releaseDate	2005-09-26
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:359744] R-HSA-164423.7
summation	[Summation:164425] ChREBP (Carbohydrate Response Element Binding Protein) doubl...
(hasEvent)	[Pathway:163358] PKA-mediated phosphorylation of key metabolic factors [Homo sapiens]
(precedingEvent)	[Reaction:163676] Phosphorylation of pChREBP (Thr 653) at Ser(196) by PKA [Homo sapiens]
(updatedInstance)	[_UpdateTracker:9781262] Update Tracker - [Reaction:164423] PhosphoChREBP (Thr 666) is exported to cytosol - v61:[addLiteratureReference, modifyText] [_UpdateTracker:9846603] Update Tracker - [Reaction:164423] PhosphoChREBP (Thr 653) is exported to cytosol - v84:[modifyText]
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