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Details on Person The protein kinase A (PKA) regulatory subunit isoforms diffe...
| Class:Id | Summation:164375 |
|---|---|
| _displayName | The protein kinase A (PKA) regulatory subunit isoforms diffe... |
| _timestamp | 2018-11-06 15:54:28 |
| created | [InstanceEdit:164336] Gopinathrao, G, 2005-05-18 22:14:39 |
| modified | [InstanceEdit:165156] Gopinathrao, G, 2005-07-29 21:00:28 [InstanceEdit:375559] Jassal, B, 2008-09-04 10:41:54 [InstanceEdit:9617580] Orlic-Milacic, Marija, 2018-08-28 [InstanceEdit:9628159] Orlic-Milacic, Marija, 2018-11-06 [InstanceEdit:9628160] Orlic-Milacic, Marija, 2018-11-06 |
| text | The protein kinase A (PKA) regulatory subunit isoforms differ in their tissue specificity and functional characteristics. The specific isoform activated in response to glucagon signaling is not known. The PKA kinase is a tetramer of two regulatory and two catalytic subunits. The regulatory subunits block the catalytic subunits. Binding of cAMP to the regulatory subunit triggers dissociation of the tetramer into two active dimers made up of a regulatory and a catalytic subunit. |
| (summation) | [Reaction:111925] cAMP induces dissociation of inactive PKA tetramers [Homo sapiens] |
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No pathways have been reviewed or authored by The protein kinase A (PKA) regulatory subunit isoforms diffe... (164375)
