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Details on Person Constitutive activation of fibroblast growth factor receptor 3 by the transmembrane domain point mutation found in achondroplasia

Class:IdLiteratureReference:1637852
_displayNameConstitutive activation of fibroblast growth factor receptor 3 by the transmembrane domain point mutation found in achondroplasia
_timestamp2011-10-05 18:32:52
author[Person:1629818] Webster, MK
[Person:190965] Donoghue, DJ
created[InstanceEdit:1637854] Rothfels, K, 2011-10-05
journalEMBO J
modified[InstanceEdit:1637881] Rothfels, K, 2011-10-05
pages520-7
pubMedIdentifier8599935
titleConstitutive activation of fibroblast growth factor receptor 3 by the transmembrane domain point mutation found in achondroplasia
volume15
year1996
(literatureReference)[EntityWithAccessionedSequence:1614398] FGFR3 G380R [plasma membrane] [Homo sapiens]
[EntityWithAccessionedSequence:2018740] FGFR3 G382D [plasma membrane] [Homo sapiens]
[EntityWithAccessionedSequence:2018743] FGFR3b G697C [plasma membrane] [Homo sapiens]
[Pathway:1226099] Signaling by FGFR in disease [Homo sapiens]
[Pathway:1839130] Signaling by activated point mutants of FGFR3 [Homo sapiens]
[Reaction:2033476] Dimerization of FGFR3 point mutants with enhanced kinase activity [Homo sapiens]
[Reaction:2033485] Autocatalytic phosphorylation of FGFR3 point mutants with enhanced kinase activity [Homo sapiens]
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