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Details on Person D-fructose 6-phosphate + D-erythrose 4-phosphate <=> sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate

Class:Id	Reaction:163764
_displayName	D-fructose 6-phosphate + D-erythrose 4-phosphate <=> sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate
_doRelease	TRUE
_timestamp	2025-01-06 08:50:56
catalystActivity	[CatalystActivity:71333] transaldolase activity of TALDO1 dimer [cytosol]
catalystActivityReference	[CatalystActivityReference:9643115] sedoheptulose-7-phosphate:D-glyceraldehyde-3-phosphate glyceronetransferase activity of TALDO1 dimer [cytosol] The three-dimensional structure of human transaldolase
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:163728] Gopinathrao, G, 2005-05-06 17:09:17
crossReference	[DatabaseIdentifier:9934060] RHEA:17055
input	[SimpleEntity:29512] Fru(6)P [cytosol] [SimpleEntity:29878] E4P [cytosol]
literatureReference	[LiteratureReference:467367] Cloning and expression of the human gene for transaldolase. A novel highly repetitive element constitutes an integral part of the coding sequence [LiteratureReference:5659967] The three-dimensional structure of human transaldolase [LiteratureReference:71326] Transaldolase deficiency: liver cirrhosis associated with a new inborn error in the pentose phosphate pathway.
modified	[InstanceEdit:164336] Gopinathrao, G, 2005-05-18 22:14:39 [InstanceEdit:166004] Gopinathrao, G, 2005-08-12 11:14:59 [InstanceEdit:199798] D'Eustachio, P, 2007-07-12 14:26:41 [InstanceEdit:467366] D'Eustachio, P, 2010-01-24 [InstanceEdit:469645] D'Eustachio, P, 2010-01-25 [InstanceEdit:5659966] D'Eustachio, Peter, 2015-01-02 [InstanceEdit:8946993] Shorser, Solomon, 2016-11-07 [InstanceEdit:9643047] Wu, G, 2019-04-04 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08 [InstanceEdit:9934059] Stephan, Ralf, 2025-01-06
name	D-fructose 6-phosphate + D-erythrose 4-phosphate <=> sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate TALDO1 transforms Fru(6)P and E4P to sedoheptulose 7-phosphate and GA3P
output	[SimpleEntity:29882] SH7P [cytosol] [SimpleEntity:29578] GA3P [cytosol]
precedingEvent	[Reaction:70471] GPI dimer isomerizes G6P [Homo sapiens] [Reaction:70420] HK1,2,3,GCK,HKDC1 phosphorylate Glc to form G6P [Homo sapiens] [Reaction:5696021] ADPGK:Mg2+ phosphorylates Glc to G6P [Homo sapiens]
releaseDate	2005-09-26
reverseReaction	[Reaction:71334] sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate <=> D-erythrose 4-phosphate + D-fructose 6-phosphate [Homo sapiens] [Reaction:163764] D-fructose 6-phosphate + D-erythrose 4-phosphate <=> sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate [Homo sapiens]
reviewStatus	[ReviewStatus:9821382] five stars
revised	[InstanceEdit:469644] D'Eustachio, P, 2010-01-24
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:358678] R-HSA-163764.5
summation	[Summation:178631] Dimeric cytosolic transaldolase (TALDO1) catalyzes the rever...
(hasEvent)	[Pathway:71336] Pentose phosphate pathway [Homo sapiens] [Pathway:163754] Insulin effects increased synthesis of Xylulose-5-Phosphate [Homo sapiens]
(normalReaction)	[FailedReaction:5659998] Defective TALDO1 does not transform Fru(6)P, E4P to SH7P, GA3P [Homo sapiens]
(precedingEvent)	[Reaction:163741] D-glyceraldehyde 3-phosphate + sedoheptulose 7-phosphate<=> xylulose 5-phosphate+ribose 5-phosphate [Homo sapiens]
(reverseReaction)	[Reaction:71334] sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate <=> D-erythrose 4-phosphate + D-fructose 6-phosphate [Homo sapiens]
(updatedInstance)	[_UpdateTracker:9784967] Update Tracker - [Reaction:163764] D-fructose 6-phosphate + D-erythrose 4-phosphate <=> sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate - v52:[addLiteratureReference, modifyText] [_UpdateTracker:9790959] Update Tracker - [Reaction:163764] D-fructose 6-phosphate + D-erythrose 4-phosphate <=> sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate - v32:[addLiteratureReference, modifyText] [_UpdateTracker:9792270] Update Tracker - [Reaction:163764] D-fructose 6-phosphate + D-erythrose 4-phosphate <=> sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate - v22:[addLiteratureReference] [_UpdateTracker:9864120] Update Tracker - [Reaction:163764] D-fructose 6-phosphate + D-erythrose 4-phosphate <=> sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate - v88:[modifyText]
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No pathways have been reviewed or authored by D-fructose 6-phosphate + D-erythrose 4-phosphate <=> sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate (163764)