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Details on Person Activated rat HSL at the lipid particle hydrolyzes triacylgl...
| Class:Id | Summation:163589 |
|---|---|
| _displayName | Activated rat HSL at the lipid particle hydrolyzes triacylgl... |
| _timestamp | 2005-05-26 18:23:32 |
| created | [InstanceEdit:163566] D'Eustachio, P, 2005-05-02 18:38:43 |
| literatureReference | [LiteratureReference:163584] Hormone-sensitive lipase of rat adipose tissue. Purification and some properties. [LiteratureReference:163454] Lipolysis: more than just a lipase |
| modified | [InstanceEdit:164560] D'Eustachio, P, 2005-05-26 18:22:14 |
| text | Activated rat HSL at the lipid particle hydrolyzes triacylglycerol to yield diacylglycerol + fatty acid. In vitro, activated partially purified HSL catalyzes this reaction at only about two times the rate measured with non-activated enzyme (Fredrikson et al. 1981). The much greater rate increase caused by HSL phosphorylation in vivo appears to be due to its phosphorylation-dependent translocation to the surface of the lipid particle (Birnbaum 2003). HSL-mediated triacylglycerol hydrolysis in humans has not been studied in detail, so the human reaction is inferred from the well-studied rat one. |
| (summation) | [Reaction:163515] triacylglycerol + H2O -> diacylglycerol + fatty acid [Rattus norvegicus] [Reaction:163551] triacylglycerol + H2O -> diacylglycerol + fatty acid [Homo sapiens] |
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No pathways have been reviewed or authored by Activated rat HSL at the lipid particle hydrolyzes triacylgl... (163589)
