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Details on Person Phosphorylated HSL dimer translocates from the cytosol to the lipid particle

Class:IdBlackBoxEvent:163554
_displayNamePhosphorylated HSL dimer translocates from the cytosol to the lipid particle
_doReleaseTRUE
_timestamp2025-07-18 19:07:56
authored[InstanceEdit:163566] D'Eustachio, P, 2005-05-02 18:38:43
compartment[Compartment:70101] cytosol
[Compartment:13977] lipid droplet
created[InstanceEdit:163566] D'Eustachio, P, 2005-05-02 18:38:43
edited[InstanceEdit:165080] D'Eustachio, P, 0000-00-00 00:00:00
goBiologicalProcess[GO_BiologicalProcess:3446241] protein localization to lipid droplet
inferredFrom
input[Complex:163513] phosphorylated HSL dimer [cytosol] [Homo sapiens]
literatureReference[LiteratureReference:163569] Mutational analysis of the hormone-sensitive lipase translocation reaction in adipocytes
[LiteratureReference:163555] Perilipin A is essential for the translocation of hormone-sensitive lipase during lipolytic activation
[LiteratureReference:163593] Translocation of hormone-sensitive lipase and perilipin upon lipolytic stimulation of rat adipocytes
[LiteratureReference:9961062] Molecular determinants for the association of human hormone-sensitive lipase with lipid droplets
modified[InstanceEdit:164563] D'Eustachio, P, 2005-05-26 18:24:44
[InstanceEdit:1043153] Wu, G, 2010-11-19
[InstanceEdit:8946993] Shorser, Solomon, 2016-11-07
[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
[InstanceEdit:9961065] D'Eustachio, Peter, 2025-07-18
namePhosphorylated HSL dimer translocates from the cytosol to the lipid particle
output[Complex:163435] phosphorylated HSL dimer [lipid droplet] [Homo sapiens]
precedingEvent
releaseDate2005-06-13
reviewStatus[ReviewStatus:9821382] five stars
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:359619] R-HSA-163554.4
summation[Summation:163481] In primary adipocytes from young rats and in adipocytes deri...
(hasEvent)[Pathway:163560] Triglyceride catabolism [Homo sapiens]
(precedingEvent)[Reaction:163549] phosphorylated HSL dimer + FABP4 -> phosphorylated HSL dimer:FABP4 complex [Homo sapiens]
(updatedInstance)[_UpdateTracker:9964669] Update Tracker - [BlackBoxEvent:163554] Phosphorylated HSL dimer translocates from the cytosol to the lipid particle - v94:[modifyText, removeLiteratureReference]
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