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Details on Person diacylglycerol + H2O -> 2-acylglycerol + fatty acid

Class:Id	Reaction:163402
_displayName	diacylglycerol + H2O -> 2-acylglycerol + fatty acid
_doRelease	TRUE
_timestamp	2025-08-13 21:47:37
authored	[InstanceEdit:163566] D'Eustachio, P, 2005-05-02 18:38:43
catalystActivity	[CatalystActivity:163604] lipase activity of phosphorylated HSL dimer:FABP4 complex [lipid droplet]
compartment	[Compartment:70101] cytosol [Compartment:13977] lipid droplet
created	[InstanceEdit:163566] D'Eustachio, P, 2005-05-02 18:38:43
crossReference	[DatabaseIdentifier:9958497] RHEA:33276
edited	[InstanceEdit:165080] D'Eustachio, P, 0000-00-00 00:00:00
inferredFrom	[Reaction:163440] diacylglycerol + H2O -> 2-acylglycerol + fatty acid [Rattus norvegicus]
input	[SimpleEntity:163414] DAG [lipid droplet] [SimpleEntity:29356] H2O [cytosol]
internalReviewed	[InstanceEdit:9958501] D'Eustachio, Peter, 2025-06-20
modified	[InstanceEdit:164563] D'Eustachio, P, 2005-05-26 18:24:44 [InstanceEdit:1043153] Wu, G, 2010-11-19 [InstanceEdit:8946993] Shorser, Solomon, 2016-11-07 [InstanceEdit:8980655] D'Eustachio, Peter, 2017-02-28 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08 [InstanceEdit:9958494] D'Eustachio, Peter, 2025-06-20 [InstanceEdit:9958500] D'Eustachio, Peter, 2025-06-20 [InstanceEdit:9963237] D'Eustachio, Peter, 2025-08-13
name	diacylglycerol + H2O -> 2-acylglycerol + fatty acid a 1,2-diacyl-sn-glycerol + H2O => a 2-acylglycerol + a fatty acid + H(+)
output	[SimpleEntity:163580] 2-acylglycerol [lipid droplet] [SimpleEntity:8876730] LCFA(-) [cytosol] [SimpleEntity:70106] H+ [cytosol]
precedingEvent	[Reaction:163551] triacylglycerol + H2O -> diacylglycerol + fatty acid [Homo sapiens] [Reaction:163549] phosphorylated HSL dimer + FABP4 -> phosphorylated HSL dimer:FABP4 complex [Homo sapiens]
previousReviewStatus	[ReviewStatus:9821385] four stars
releaseDate	2005-06-13
reviewed	[InstanceEdit:9963238] Hill, David P, 2025-08-13
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:361339] R-HSA-163402.5
structureModified	[InstanceEdit:9958494] D'Eustachio, Peter, 2025-06-20
summation	[Summation:163552] Rat HSL catalyzes the hydrolysis of diacylglycerol to yield ...
(hasEvent)	[Pathway:163560] Triglyceride catabolism [Homo sapiens]
(precedingEvent)	[Reaction:163595] 2-acylglycerol + H2O -> glycerol + fatty acid [Homo sapiens] [Reaction:5334794] FABPs bind LCFAs [Homo sapiens]
(updatedInstance)	[_UpdateTracker:9781615] Update Tracker - [Reaction:163402] diacylglycerol + H2O -> 2-acylglycerol + fatty acid - v60:[add_removeOutput] [_UpdateTracker:9964762] Update Tracker - [Reaction:163402] diacylglycerol + H2O -> 2-acylglycerol + fatty acid - v94:[removeOutput]
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No pathways have been reviewed or authored by diacylglycerol + H2O -> 2-acylglycerol + fatty acid (163402)