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Details on Person Plk1 regulates activation of the anaphase promoting complex by phosphorylating and triggering SCFbetaTrCP-dependent destruction of the APC Inhibitor Emi1

Class:Id	LiteratureReference:163011
_displayName	Plk1 regulates activation of the anaphase promoting complex by phosphorylating and triggering SCFbetaTrCP-dependent destruction of the APC Inhibitor Emi1
_timestamp	2006-05-19 19:29:25
author	[Person:163020] Hansen, DV [Person:163012] Loktev, AV [Person:163041] Ban, KH
created	[InstanceEdit:163007] Gillespie, ME, 2005-04-12 04:40:16
journal	Mol Biol Cell
modified	[InstanceEdit:180405] D'Eustachio, P, 2006-05-19 19:28:52
pages	5623-34
pubMedIdentifier	15469984
title	Plk1 regulates activation of the anaphase promoting complex by phosphorylating and triggering SCFbetaTrCP-dependent destruction of the APC Inhibitor Emi1
volume	15
year	2004
(literatureReference)	[Summation:163025] During the early stages of mitosis, Cdc2 and PLK1 cooperate ... [Summation:174182] Cdk mediated phosphorylation of Emi1 is believed to promotes... [Reaction:174159] Ubiquitination of Emi1 by SCF-beta-TrCP [Homo sapiens] [Reaction:174174] Phosphorylation of the Emi1 DSGxxS degron by Plk1 [Homo sapiens] [BlackBoxEvent:174203] SCF-mediated degradation of Emi1 [Homo sapiens]
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No pathways have been reviewed or authored by Plk1 regulates activation of the anaphase promoting complex by phosphorylating and triggering SCFbetaTrCP-dependent destruction of the APC Inhibitor Emi1 (163011)