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Details on Person glucosaminyl-acyl-PI + dolichol phosphate D-mannose -> mannose(al1-4)glucosaminyl-acyl-PI + dolichol phosphate

Class:Id	Reaction:162830
_displayName	glucosaminyl-acyl-PI + dolichol phosphate D-mannose -> mannose(al1-4)glucosaminyl-acyl-PI + dolichol phosphate
_doRelease	TRUE
_timestamp	2016-11-10 00:56:42
authored	[InstanceEdit:162789] D'Eustachio, P, 2005-04-04 21:01:34
catalystActivity	[CatalystActivity:162859] mannosyltransferase activity of GPI mannosyltransferase I [endoplasmic reticulum membrane]
compartment	[Compartment:12045] endoplasmic reticulum membrane
created	[InstanceEdit:162789] D'Eustachio, P, 2005-04-04 21:01:34
edited	[InstanceEdit:165080] D'Eustachio, P, 0000-00-00 00:00:00
input	[SimpleEntity:8855665] glucosaminyl-acyl-PI [lumenal side of endoplasmic reticulum membrane] [SimpleEntity:449229] DOLP-Man [lumenal side of endoplasmic reticulum membrane]
literatureReference	[LiteratureReference:162882] PIG-M transfers the first mannose to glycosylphosphatidylinositol on the lumenal side of the ER [LiteratureReference:162828] Mammalian PIG-X and yeast Pbn1p are the essential components of glycosylphosphatidylinositol-mannosyltransferase I
modified	[InstanceEdit:162887] D'Eustachio, P, 2005-04-04 21:15:36 [InstanceEdit:163835] D'Eustachio, P, 2005-05-07 21:30:29 [InstanceEdit:164450] D'Eustachio, P, 2005-05-19 19:27:35 [InstanceEdit:4789871] Jassal, B, 2013-10-28 [InstanceEdit:8855658] D'Eustachio, Peter, 2016-02-04 [InstanceEdit:8946993] Shorser, Solomon, 2016-11-07 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	glucosaminyl-acyl-PI + dolichol phosphate D-mannose -> mannose(al1-4)glucosaminyl-acyl-PI + dolichol phosphate
output	[SimpleEntity:8855659] mannose (a1-4) glucosaminyl-acyl-PI [lumenal side of endoplasmic reticulum membrane] [SimpleEntity:162872] dolichyl phosphate [endoplasmic reticulum membrane]
precedingEvent	[Reaction:162683] glucosaminyl-PI + fatty acyl-CoA -> glucosaminyl-acyl-PI + CoA-SH [Homo sapiens] [Reaction:162857] N-acetylglucosaminyl-PI + H2O -> glucosaminyl-PI + acetate [Homo sapiens] [Reaction:162715] Reorientation of dolichyl phosphate D-mannose in the endoplasmic reticulum membrane [Homo sapiens] [Reaction:162721] dolichyl phosphate + GDP-alpha-D-mannose -> dolichyl phosphate D-mannose [Homo sapiens]
releaseDate	2005-04-11
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:360811] R-HSA-162830.4
summation	[Summation:162862] In the fifth step of GPI synthesis, a mannose residue is add...
(hasEvent)	[Pathway:162710] Synthesis of glycosylphosphatidylinositol (GPI) [Homo sapiens]
(precedingEvent)	[Reaction:162798] mannose(a1-4)glucosaminyl-acyl-PI + phosphatidylethanolamine -> (ethanolamineP) mannose(al1-4)glucosaminyl-acyl-PI + diacylglycerol [Homo sapiens]
(updatedInstance)	[_UpdateTracker:9783475] Update Tracker - [Reaction:162830] glucosaminyl-acyl-PI + dolichol phosphate D-mannose -> mannose(al1-4)glucosaminyl-acyl-PI + dolichol phosphate - v56:[add_removeInput, add_removeOutput] [_UpdateTracker:9786904] Update Tracker - [Reaction:162830] glucosaminyl-acyl-PI + dolichol phosphate D-mannose -> mannose(al1-4)glucosaminyl-acyl-PI + dolichol phosphate - v47:[add_removeInput]
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No pathways have been reviewed or authored by glucosaminyl-acyl-PI + dolichol phosphate D-mannose -> mannose(al1-4)glucosaminyl-acyl-PI + dolichol phosphate (162830)