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Details on Person phosphatidylinositol + UDP-N-acetyl-D-glucosamine -> N-acetylglucosaminyl-PI + UDP

Class:IdReaction:162730
_displayNamephosphatidylinositol + UDP-N-acetyl-D-glucosamine -> N-acetylglucosaminyl-PI + UDP
_doReleaseTRUE
_timestamp2022-03-01 22:45:27
authored[InstanceEdit:162789] D'Eustachio, P, 2005-04-04 21:01:34
catalystActivity[CatalystActivity:162711] UDP-glycosyltransferase activity of GPI-GnT [endoplasmic reticulum membrane]
compartment[Compartment:70101] cytosol
[Compartment:12045] endoplasmic reticulum membrane
created[InstanceEdit:162789] D'Eustachio, P, 2005-04-04 21:01:34
edited[InstanceEdit:165080] D'Eustachio, P, 0000-00-00 00:00:00
input[SimpleEntity:426639] PI [endoplasmic reticulum membrane]
[SimpleEntity:162756] UDP-GlcNAc [cytosol]
literatureReference[LiteratureReference:9012977] The initial enzyme for glycosylphosphatidylinositol biosynthesis requires PIG-Y, a seventh component
[LiteratureReference:162842] PIG-A and PIG-H, which participate in glycosylphosphatidylinositol anchor biosynthesis, form a protein complex in the endoplasmic reticulum
[LiteratureReference:162794] The first step of glycosylphosphatidylinositol biosynthesis is mediated by a complex of PIG-A, PIG-H, PIG-C and GPI1
[LiteratureReference:162736] Initial enzyme for glycosylphosphatidylinositol biosynthesis requires PIG-P and is regulated by DPM2
modified[InstanceEdit:163835] D'Eustachio, P, 2005-05-07 21:30:29
[InstanceEdit:164451] D'Eustachio, P, 2005-05-19 19:28:21
[InstanceEdit:1043153] Wu, G, 2010-11-19
[InstanceEdit:3785731] D'Eustachio, P, 2013-07-03
[InstanceEdit:8855658] D'Eustachio, Peter, 2016-02-04
[InstanceEdit:8946993] Shorser, Solomon, 2016-11-07
[InstanceEdit:9012976] D'Eustachio, Peter, 2017-07-21
[InstanceEdit:9767886] D'Eustachio, Peter, 2022-03-01
[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
namephosphatidylinositol + UDP-N-acetyl-D-glucosamine -> N-acetylglucosaminyl-PI + UDP
output[SimpleEntity:8855657] N-acetylglucosaminyl-PI [cytoplasmic side of endoplasmic reticulum membrane]
[SimpleEntity:110096] UDP [cytosol]
[SimpleEntity:70106] H+ [cytosol]
releaseDate2005-04-11
reviewStatus[ReviewStatus:9821382] five stars
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:359813] R-HSA-162730.6
summation[Summation:162757] The first step of GPI synthesis is the transfer of N-acetylg...
(hasEvent)[Pathway:162710] Synthesis of glycosylphosphatidylinositol (GPI) [Homo sapiens]
(inferredFrom)[Reaction:1113230] phosphatidylinositol + UDP-N-acetyl-D-glucosamine -> N-acetylglucosaminyl-PI + UDP [Oryza sativa]
(orthologousEvent)[Reaction:1113230] phosphatidylinositol + UDP-N-acetyl-D-glucosamine -> N-acetylglucosaminyl-PI + UDP [Oryza sativa]
(precedingEvent)[Reaction:162857] N-acetylglucosaminyl-PI + H2O -> glucosaminyl-PI + acetate [Homo sapiens]
(updatedInstance)[_UpdateTracker:9774928] Update Tracker - [Reaction:162730] phosphatidylinositol + UDP-N-acetyl-D-glucosamine -> N-acetylglucosaminyl-PI + UDP - v80:[addOutput]
[_UpdateTracker:9780511] Update Tracker - [Reaction:162730] phosphatidylinositol + UDP-N-acetyl-D-glucosamine -> N-acetylglucosaminyl-PI + UDP - v62:[addLiteratureReference, modifyText]
[_UpdateTracker:9783620] Update Tracker - [Reaction:162730] phosphatidylinositol + UDP-N-acetyl-D-glucosamine -> N-acetylglucosaminyl-PI + UDP - v56:[add_removeOutput]
[_UpdateTracker:9787083] Update Tracker - [Reaction:162730] phosphatidylinositol + UDP-N-acetyl-D-glucosamine -> N-acetylglucosaminyl-PI + UDP - v46:[add_removeInput]
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No pathways have been reviewed or authored by phosphatidylinositol + UDP-N-acetyl-D-glucosamine -> N-acetylglucosaminyl-PI + UDP (162730)
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