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Details on Person Sulfate is exported to the cytosol in exchange for dicarboxylate

Class:IdReaction:1614546
_displayNameSulfate is exported to the cytosol in exchange for dicarboxylate
_doReleaseTRUE
_timestamp2025-08-13 18:10:16
authored[InstanceEdit:1237120] Stephan, R, 2010-10-24
catalystActivity[CatalystActivity:372844] dicarboxylic acid transmembrane transporter activity of SLC25A10 [mitochondrial inner membrane]
compartment[Compartment:70616] mitochondrial inner membrane
[Compartment:70101] cytosol
[Compartment:5460] mitochondrial matrix
created[InstanceEdit:1614621] Jassal, Bijay, 2011-09-29
crossReference[DatabaseIdentifier:9930110] RHEA:71615
edited[InstanceEdit:1614621] Jassal, Bijay, 2011-09-29
input[SimpleEntity:198498] MAL [cytosol]
[SimpleEntity:1614584] SO4(2-) [mitochondrial matrix]
isChimericFALSE
literatureReference[LiteratureReference:372842] Organization and sequence of the gene for the human mitochondrial dicarboxylate carrier: evolution of the carrier family
[LiteratureReference:1614559] The transport of sulphate and sulphite in rat liver mitochondria
modified[InstanceEdit:1619464] Jassal, Bijay, 2011-09-30
[InstanceEdit:1660488] Jassal, Bijay, 2011-10-13
[InstanceEdit:8946993] Shorser, Solomon, 2016-11-07
[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
[InstanceEdit:9930119] D'Eustachio, Peter, 2024-12-02
[InstanceEdit:9963193] Stephan, Ralf, 2025-08-13
nameSulfate is exported to the cytosol in exchange for dicarboxylate
(S)-malate(in) + sulfate(out) = (S)-malate(out) + sulfate(in)
output[SimpleEntity:113544] MAL [mitochondrial matrix]
[SimpleEntity:174375] SO4(2-) [cytosol]
precedingEvent
releaseDate2011-12-06
reviewed[InstanceEdit:1660489] D'Eustachio, P, 2011-10-13
reviewStatus[ReviewStatus:9821382] five stars
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:2016233] R-HSA-1614546.5
summation[Summation:1614548] Sulfate leaves the mitochondrion with the help of the dicarb...
(hasEvent)[Pathway:428643] Organic anion transport by SLC5/17/25 transporters [Homo sapiens]
[Pathway:1614517] Sulfide oxidation to sulfate [Homo sapiens]
(precedingEvent)[Reaction:198440] SLC25A11 exchanges malate and alpha-ketoglutarate (2-oxoglutarate) across the inner mitochondrial membrane [Homo sapiens]
[Reaction:372843] SLC25A10 mediates exchange of malate and phosphate [Homo sapiens]
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