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Details on Person FGFR4 V550L [plasma membrane]

Class:Id	EntityWithAccessionedSequence:1614436
_displayName	FGFR4 V550L [plasma membrane]
_timestamp	2014-11-20 17:29:48
compartment	[Compartment:876] plasma membrane
created	[InstanceEdit:1614437] Rothfels, K, 2011-09-28
disease	[Disease:1614291] rhabdomyosarcoma
endCoordinate	802
hasModifiedResidue	[ReplacedResidue:1614435] L-valine 550 replaced with L-leucine
literatureReference	[LiteratureReference:2038923] Identification of FGFR4-activating mutations in human rhabdomyosarcomas that promote metastasis in xenotransplanted models
modified	[InstanceEdit:2018717] Rothfels, K, 2011-11-24 [InstanceEdit:2038956] Rothfels, K, 2012-01-10 [InstanceEdit:5649577] Rothfels, Karen, 2014-11-20
name	FGFR4 V550L
referenceEntity	[ReferenceGeneProduct:54820] UniProt:P22455 FGFR4 [Homo sapiens]
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:2295994] R-HSA-1614436.1
startCoordinate	22
(hasCandidate)	[CandidateSet:2038948] FGFR4 enhanced kinase mutants [plasma membrane] [Homo sapiens]
(hasComponent)	[Complex:2038929] FGFR4 V550L mutant dimer [plasma membrane] [Homo sapiens]
(updatedInstance)	[_UpdateTracker:9892047] Update Tracker - [EntityWithAccessionedSequence:1614436] FGFR4 V550L [plasma membrane] - v52:[modifyName]
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No pathways have been reviewed or authored by FGFR4 V550L [plasma membrane] (1614436)