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Details on Person GLB1 hydrolyzes SapB/C:LacCer

Class:IdReaction:1606312
_displayNameGLB1 hydrolyzes SapB/C:LacCer
_doReleaseTRUE
_timestamp2023-08-03 09:06:13
authored[InstanceEdit:1605804] Jassal, Bijay, 2011-09-21
catalystActivity[CatalystActivity:1605789] beta-galactosidase activity of BGAL [lysosomal lumen]
compartment[Compartment:161320] lysosomal lumen
created[InstanceEdit:1606314] Jassal, Bijay, 2011-09-21
edited[InstanceEdit:1605804] Jassal, Bijay, 2011-09-21
input[SimpleEntity:1605715] H2O [lysosomal lumen]
[DefinedSet:9840969] Sap B/C:LacCer [lysosomal lumen] [Homo sapiens]
isChimericFALSE
literatureReference[LiteratureReference:1605727] Human small-intestinal beta-galactosidases. Separation and characterization of one lactase and one hetero beta-galactosidase
[LiteratureReference:9840312] Emerging concepts of ganglioside metabolism
[LiteratureReference:9840817] Prosaposin deficiency: further characterization of the sphingolipid activator protein-deficient sibs. Multiple glycolipid elevations (including lactosylceramidosis), partial enzyme deficiencies and ultrastructure of the skin in this generalized sphingolipid storage disease
modified[InstanceEdit:1606563] Jassal, Bijay, 2011-09-23
[InstanceEdit:1660664] Jassal, B, 2011-10-14
[InstanceEdit:1660680] Jassal, B, 2011-10-14
[InstanceEdit:1863069] Jassal, Bijay, 2011-10-31
[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
[InstanceEdit:9840967] Stephan, Ralf, 2023-08-03
nameGLB1 hydrolyzes SapB/C:LacCer
output[SimpleEntity:1605637] Gal [lysosomal lumen]
[DefinedSet:9840964] Sap B/C:GlcCer [lysosomal lumen] [Homo sapiens]
precedingEvent
releaseDate2011-12-06
reviewed[InstanceEdit:1863068] Stephan, Ralf, 2011-10-31
reviewStatus[ReviewStatus:9821382] five stars
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:2016163] R-HSA-1606312.3
summation[Summation:1606313] Lactosylceramide (LacCer) is the central intermediate in gly...
(hasEvent)[Pathway:9840310] Glycosphingolipid catabolism [Homo sapiens]
(precedingEvent)[Reaction:1605591] GBA1:SAPC hydrolyzes GlcCer [Homo sapiens]
(updatedInstance)[_UpdateTracker:9842313] Update Tracker - [Reaction:1606312] GLB1 hydrolyzes SapB/C:LacCer - v86:[addLiteratureReference, add_removeInput, add_removeOutput, modifyText]
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