Query author contributions in Reactome

Reactome depends on collaboration between our curation team and outside experts to assemble and peer-review its pathway modules. The integration of ORCID within Reactome enables us to meet a key challenge with authoring, curating and reviewing biological information by incentivizing and crediting the external experts that contribute their expertise and time to the Reactome curation process. More information is available at ORCID and Reactome.

If you have an ORCID ID that is not listed on this page, please forward this information to us and we will update your Reactome pathway records.

Details on Person SMPD4 hydrolyzes sphingomyelin (ER membrane)

Class:Id	Reaction:1606288
_displayName	SMPD4 hydrolyzes sphingomyelin (ER membrane)
_doRelease	TRUE
_timestamp	2023-08-17 14:46:01
authored	[InstanceEdit:1605804] Jassal, Bijay, 2011-09-21
catalystActivity	[CatalystActivity:1606279] sphingomyelin phosphodiesterase activity of SMPD4:Mg2+ [endoplasmic reticulum membrane]
compartment	[Compartment:17957] endoplasmic reticulum lumen [Compartment:12045] endoplasmic reticulum membrane
created	[InstanceEdit:1606282] Jassal, B, 2011-09-21
edited	[InstanceEdit:1605804] Jassal, Bijay, 2011-09-21
input	[SimpleEntity:1606283] SPHM d18:1 [endoplasmic reticulum membrane] [SimpleEntity:113519] H2O [endoplasmic reticulum lumen]
isChimeric	FALSE
literatureReference	[LiteratureReference:1606286] Novel tumor necrosis factor-responsive mammalian neutral sphingomyelinase-3 is a C-tail-anchored protein [LiteratureReference:9841229] Loss of SMPD4 Causes a Developmental Disorder Characterized by Microcephaly and Congenital Arthrogryposis
modified	[InstanceEdit:1606314] Jassal, Bijay, 2011-09-21 [InstanceEdit:1606563] Jassal, Bijay, 2011-09-23 [InstanceEdit:1863069] Jassal, Bijay, 2011-10-31 [InstanceEdit:1864087] Jassal, B, 2011-10-31 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08 [InstanceEdit:9841226] Stephan, Ralf, 2023-08-11 [InstanceEdit:9842060] Stephan, Ralf, 2023-08-17 [InstanceEdit:9842093] Stephan, Ralf, 2023-08-17
name	SMPD4 hydrolyzes sphingomyelin (ER membrane)
output	[SimpleEntity:428256] CERA [endoplasmic reticulum membrane] [SimpleEntity:1606280] ChoP [endoplasmic reticulum lumen] [SimpleEntity:70106] H+ [cytosol]
previousReviewStatus	[ReviewStatus:9821384] two stars
releaseDate	2011-12-06
reviewed	[InstanceEdit:1863068] Stephan, Ralf, 2011-10-31 [InstanceEdit:9842094] D'Eustachio, Peter, 2023-08-17
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:2016630] R-HSA-1606288.3
structureModified	[InstanceEdit:9842060] Stephan, Ralf, 2023-08-17
summation	[Summation:1606285] ER membrane-bound sphingomyelin phosphodiesterase 4 (SMPD4) ...
(hasEvent)	[Pathway:9840310] Glycosphingolipid catabolism [Homo sapiens]
(precedingEvent)	[Reaction:428231] ACER1 hydrolyzes ceramide (endoplasmic reticulum) [Homo sapiens]
(updatedInstance)	[_UpdateTracker:9842254] Update Tracker - [Reaction:1606288] SMPD4 hydrolyzes sphingomyelin (ER membrane) - v86:[addLiteratureReference, addOutput, modifyText]
[Change default viewing format]

No pathways have been reviewed or authored by SMPD4 hydrolyzes sphingomyelin (ER membrane) (1606288)