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Details on Person Ganglioside GA1 (asialo-GM1, ganglio-N-tetraosylceramide) is...
| Class:Id | Summation:1605722 |
|---|---|
| _displayName | Ganglioside GA1 (asialo-GM1, ganglio-N-tetraosylceramide) is... |
| _timestamp | 2023-10-09 09:10:14 |
| created | [InstanceEdit:1605804] Jassal, Bijay, 2011-09-21 |
| modified | [InstanceEdit:1605814] Jassal, B, 2011-09-21 [InstanceEdit:9840647] Stephan, Ralf, 2023-07-22 [InstanceEdit:9840791] Stephan, Ralf, 2023-07-26 [InstanceEdit:9840794] Stephan, Ralf, 2023-07-27 [InstanceEdit:9846167] Stephan, Ralf, 2023-10-09 |
| text | Ganglioside GA1 (asialo-GM1, ganglio-N-tetraosylceramide) is a ganglioside that accumulates in nerve cells in GM1-gangliosidosis, showing that GA1 is hydrolyzed by GLB1, probably to GA2 (Caciotti et al., 2005). Since GLB1 acts on solubilized gangliosides, we assume GA1 and GA2 are bound to GM2A during the process. GLB1L, GLB1L2, and GLB1L3 are gene products with nearly identical protein sequences to GLB1 and may be able to perform the same function. |
| (summation) | [Reaction:9840795] Beta-galactosidases hydrolyze GM2A:GA1 to GM2A:GA2 [Homo sapiens] |
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No pathways have been reviewed or authored by Ganglioside GA1 (asialo-GM1, ganglio-N-tetraosylceramide) is... (1605722)
