Reactome: A Curated Pathway Database
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Query author contributions in Reactome

Reactome depends on collaboration between our curation team and outside experts to assemble and peer-review its pathway modules. The integration of ORCID within Reactome enables us to meet a key challenge with authoring, curating and reviewing biological information by incentivizing and crediting the external experts that contribute their expertise and time to the Reactome curation process. More information is available at ORCID and Reactome.

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Details on Person DTX4 [cytosol]

Class:IdEntityWithAccessionedSequence:1604439
_displayNameDTX4 [cytosol]
_timestamp2012-03-01 11:50:14
compartment[Compartment:70101] cytosol
created[InstanceEdit:1604440] Orlic-Milacic, M, 2011-09-15
endCoordinate619
nameDTX4
Protein deltex-4
referenceEntity[ReferenceGeneProduct:227617] UniProt:Q9Y2E6 DTX4 [Homo sapiens]
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:2159329] R-HSA-1604439.1
startCoordinate1
(activeUnit)[CatalystActivity:3249400] ubiquitin-protein transferase activity of NLRP4:DTX4:dsDNA:ZBP1:pS-172-TBK1 [cytosol]
[CatalystActivity:8948711] ubiquitin-protein transferase activity of NLRP4:DTX4:STING:p-S172-TBK1:IRF3 [cytoplasmic vesicle membrane]
(hasCandidate)[CandidateSet:1604454] DTX [cytosol] [Homo sapiens]
(hasComponent)[Complex:3249384] NLRP4:DTX4:dsDNA:ZBP1:pS-172-TBK1 [cytosol] [Homo sapiens]
[Complex:8948707] NLRP4:DTX4:STING:p-S172-TBK1:IRF3 [cytoplasmic vesicle membrane] [Homo sapiens]
(hasMember)[CandidateSet:8852046] RING-type E3 ubiquitin ligase [cytosol] [Homo sapiens]
(input)[Reaction:3249392] NLRP4 and DTX4 associate with p-S172-TBK1 within STING:TBK1:IRF3 [Homo sapiens]
[Reaction:8948703] NLRP4 and DTX4 associate with p-S172-TBK1 within dsDNA:ZBP1:TBK1 [Homo sapiens]
(output)[Reaction:3249386] DTX4 ubiquitinates p-S172-TBK1 within NLRP4:DTX4:dsDNA:ZBP1:TBK1 [Homo sapiens]
[Reaction:8948709] DTX4 ubiquitinates p-S172-TBK1 within NLRP4:DTX4:STING:TBK1:IRF3 [Homo sapiens]
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No pathways have been reviewed or authored by DTX4 [cytosol] (1604439)