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Details on Person UniProt:Q9FJV0 MKK6
| Class:Id | ReferenceGeneProduct:1601031 |
|---|---|
| _chainChangeLog | chain:1-356 added on Fri February 6 2015 |
| _displayName | UniProt:Q9FJV0 MKK6 |
| _timestamp | 2025-02-21 19:39:44 |
| chain | chain:1-356 |
| checksum | C95016C1DAE69CED |
| comment | FUNCTION The ANPs-MKK6-MPK4 module is involved in the regulation of plant cytokinesis during meiosis and mitosis. MKK6-MPK13 module positively regulates lateral root formation. Phosphorylates and activates MPK4. Activates MPK5 and MPK13 in vitro.CATALYTIC ACTIVITY L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)CATALYTIC ACTIVITY L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)CATALYTIC ACTIVITY L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+)ACTIVITY REGULATION Activated through serine and threonine phosphorylation.SUBUNIT Interacts with P.syringae type III effector HopF2. Interacts with MPK4, MPK6, MPK11 and MPK13. Interacts with ANP3.INTERACTION Localized at the equatorial plane of the phragmoplast.TISSUE SPECIFICITY Expressed in roots, stems and flower buds. Higher levels in shoot apices and flowers.PTM Phosphorylation at Ser-221 and Thr-227 by MAP kinase kinase kinases positively regulates kinase activity.DISRUPTION PHENOTYPE Plants exhibit a dwarf phenotype with fewer flowers, large cells with multiple nuclei in various organs and large malformed pollen grains. Defects in the formation of the cell plate. RNAi MKK6 displays fewer lateral roots.SIMILARITY Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase subfamily. |
| created | [InstanceEdit:1598157] Couchman, M, 2007-08-14 |
| crossReference | [DatabaseIdentifier:1599710] ATIDB:AT5G56580 [DatabaseIdentifier:1600436] TAIR:AT5G56580 [DatabaseIdentifier:1600437] MIPS:AT5G56580 [DatabaseIdentifier:1600438] TIGR:AT5G56580 |
| description | recommendedName: Mitogen-activated protein kinase kinase 6 shortName: AtMKK6 shortName: MAP kinase kinase 6 ecNumber: 2.7.12.2 alternativeName: Protein Arabidopsis NQK1 homolog |
| geneName | MKK6 ANQ1 At5g56580 MIK19.2 |
| identifier | Q9FJV0 |
| isSequenceChanged | FALSE |
| keyword | ATP-binding Cytoplasm Cytoskeleton Kinase Nucleotide-binding Phosphoprotein Reference proteome Serine/threonine-protein kinase Transferase |
| modified | [InstanceEdit:1598234] Couchman, MS [InstanceEdit:1601927] Preece, J, 2011-09-12 [InstanceEdit:1995863] Weiser, JD [InstanceEdit:2132304] Weiser, JD [InstanceEdit:2265580] Weiser, JD [InstanceEdit:5433710] Weiser, JD [InstanceEdit:5634237] Weiser, JD [InstanceEdit:5673015] Weiser, JD [InstanceEdit:9037114] Weiser, JD [InstanceEdit:9627708] Weiser, JD [InstanceEdit:9637257] Weiser, JD [InstanceEdit:9676415] Weiser, JD [InstanceEdit:9852000] Weiser, Joel, 2023-11-03 [InstanceEdit:9939033] Weiser, Joel, 2025-02-21 |
| name | MKK6 |
| otherIdentifier | AT5G56580 M2K6_ARATH M2K6 247962_at Q9FJV0 Q9FJV0_ARATH |
| referenceDatabase | [ReferenceDatabase:2] UniProt |
| secondaryIdentifier | M2K6_ARATH |
| sequenceLength | 356 |
| species | [Species:170905] Arabidopsis thaliana |
| (referenceEntity) | [EntityWithAccessionedSequence:1599103] Phospho-NQK1 [cytosol] [Arabidopsis thaliana] [EntityWithAccessionedSequence:1599314] NQK1 [cytosol] [Arabidopsis thaliana] |
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No pathways have been reviewed or authored by UniProt:Q9FJV0 MKK6 (1601031)
