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Details on Person UniProt:Q9C5V6 TOP6B
| Class:Id | ReferenceGeneProduct:1601012 |
|---|---|
| _chainChangeLog | chain:1-670 added on Sat February 7 2015 |
| _displayName | UniProt:Q9C5V6 TOP6B |
| _timestamp | 2023-11-03 18:36:01 |
| chain | chain:1-670 |
| checksum | 5735F0A6B4578D61 |
| comment | FUNCTION Component of the DNA topoisomerase VI involved in chromatin organization and progression of endoreduplication cycles. Relaxes both positive and negative superturns and exhibits a strong decatenase activity. The B subunit binds ATP. Involved in cell-elongation processes.CATALYTIC ACTIVITY ATP-dependent breakage, passage and rejoining of double-stranded DNA.SUBUNIT Homodimer. Heterotetramer of two TOP6A and two TOP6B subunits. Interacts with SPO11-2, but not with SPO11-1, RHL1 or BIN4.INTERACTION Highly expressed in leaves, stems, flowers and seedlings.DISRUPTION PHENOTYPE Plants are defective in cell elongation and show a severe dwarf phenotype.SIMILARITY Belongs to the TOP6B family. |
| created | [InstanceEdit:1598157] Couchman, M, 2007-08-14 |
| crossReference | [DatabaseIdentifier:1599779] ATIDB:AT3G20780 [DatabaseIdentifier:1600386] TAIR:AT3G20780 [DatabaseIdentifier:1600387] MIPS:AT3G20780 [DatabaseIdentifier:1600388] TIGR:AT3G20780 |
| description | recommendedName: fullName evidence="1"DNA topoisomerase 6 subunit B shortName: AtTOP6B ecNumber evidence="1"5.6.2.2 alternativeName: Protein BRASSINOSTEROID INSENSITIVE 3 alternativeName: Protein ELONGATED HYPOCOTYL 6 alternativeName: Protein ROOT HAIRLESS 3 |
| geneName | TOP6B BIN3 HYP6 RHL3 At3g20780 MOE17.8 |
| identifier | Q9C5V6 |
| isSequenceChanged | FALSE |
| keyword | ATP-binding DNA-binding Isomerase Nucleotide-binding Nucleus Reference proteome Topoisomerase |
| modified | [InstanceEdit:1598234] Couchman, MS [InstanceEdit:1601927] Preece, J, 2011-09-12 [InstanceEdit:1995863] Weiser, JD [InstanceEdit:2132304] Weiser, JD [InstanceEdit:2265580] Weiser, JD [InstanceEdit:3132113] Weiser, JD [InstanceEdit:5433710] Weiser, JD [InstanceEdit:5634237] Weiser, JD [InstanceEdit:5673015] Weiser, JD [InstanceEdit:9037114] Weiser, JD [InstanceEdit:9637257] Weiser, JD [InstanceEdit:9645038] Weiser, JD [InstanceEdit:9657908] Weiser, JD [InstanceEdit:9676415] Weiser, JD [InstanceEdit:9852000] Weiser, Joel, 2023-11-03 |
| name | TOP6B |
| otherIdentifier | AT3G20780 Q9C5V6_ARATH Q9C5V6 257982_at |
| referenceDatabase | [ReferenceDatabase:2] UniProt |
| secondaryIdentifier | TOP6B_ARATH Q9LT43 |
| sequenceLength | 670 |
| species | [Species:170905] Arabidopsis thaliana |
| (referenceEntity) | [EntityWithAccessionedSequence:1599149] RHL3 [nucleoplasm] [Arabidopsis thaliana] [EntityWithAccessionedSequence:1599433] AtTOP6B [nucleoplasm] [Arabidopsis thaliana] |
| [Change default viewing format] | |
No pathways have been reviewed or authored by UniProt:Q9C5V6 TOP6B (1601012)
