Query author contributions in Reactome
Reactome depends on collaboration between our curation team and outside experts to assemble and peer-review its pathway modules. The integration of ORCID within Reactome enables us to meet a key challenge with authoring, curating and reviewing biological information by incentivizing and crediting the external experts that contribute their expertise and time to the Reactome curation process. More information is available at ORCID and Reactome.
If you have an ORCID ID that is not listed on this page, please forward this information to us and we will update your Reactome pathway records.
Details on Person UniProt:O80786 MCM5
| Class:Id | ReferenceGeneProduct:1600994 |
|---|---|
| _chainChangeLog | chain:1-727 added on Sat February 7 2015 |
| _displayName | UniProt:O80786 MCM5 |
| _timestamp | 2025-02-21 18:38:40 |
| chain | chain:1-727 |
| checksum | 81F519BDBD73CFB3 |
| comment | FUNCTION Probable component of the MCM2-7 complex (MCM complex) that may function as a DNA helicase and which is essential to undergo a single round of replication initiation and elongation per cell cycle in eukaryotic cells.CATALYTIC ACTIVITY ATP + H2O = ADP + phosphate + H(+)SUBUNIT Component of the minichromosome maintenance (MCM) complex, a heterotetramer composed of MCM2, MCM3, MCM4, MCM5, MCM6 and MCM7. Interacts with EGT1.INTERACTION Localized in the nucleus during G1, S and G2 phases of the cell cycle, and released into the cytoplasmic compartment during mitosis.ALTERNATIVE PRODUCTS A number of isoforms are produced. According to EST sequences.TISSUE SPECIFICITY Expressed in shoot apex and flower buds.SIMILARITY Belongs to the MCM family.SEQUENCE CAUTION Sequencing errors. |
| created | [InstanceEdit:1598120] Couchman, M, 2007-07-02 |
| crossReference | [DatabaseIdentifier:1600336] ATIDB:At2g07690 [DatabaseIdentifier:1600337] TAIR:At2g07690 [DatabaseIdentifier:1600338] MIPS:At2g07690 [DatabaseIdentifier:1600339] NCBI Entrez Gene:At2g07690 [DatabaseIdentifier:1600340] TIGR:At2g07690 |
| description | recommendedName: DNA replication licensing factor MCM5 ecNumber: 3.6.4.12 alternativeName: Minichromosome maintenance protein 5 shortName: AtMCM5 |
| geneName | MCM5 At2g07690 T12J2 |
| identifier | O80786 |
| isSequenceChanged | FALSE |
| keyword | Alternative splicing ATP-binding Cell cycle Cytoplasm DNA replication DNA-binding Helicase Hydrolase Nucleotide-binding Nucleus Reference proteome |
| modified | [InstanceEdit:1598234] Couchman, MS [InstanceEdit:1601927] Preece, J, 2011-09-12 [InstanceEdit:5433710] Weiser, JD [InstanceEdit:5634237] Weiser, JD [InstanceEdit:5673015] Weiser, JD [InstanceEdit:9037114] Weiser, JD [InstanceEdit:9637257] Weiser, JD [InstanceEdit:9676415] Weiser, JD [InstanceEdit:9852000] Weiser, Joel, 2023-11-03 [InstanceEdit:9939033] Weiser, Joel, 2025-02-21 |
| name | MCM5 |
| otherIdentifier | O80786_ARATH O80786 266959_at AT2G07690 |
| referenceDatabase | [ReferenceDatabase:2] UniProt |
| secondaryIdentifier | MCM5_ARATH |
| sequenceLength | 727 |
| species | [Species:170905] Arabidopsis thaliana |
| (isoformParent) | [ReferenceIsoform:8965692] UniProt:O80786-1 MCM5 [Arabidopsis thaliana] |
| (referenceEntity) | [EntityWithAccessionedSequence:1599349] MCM5 [nucleoplasm] [Arabidopsis thaliana] |
| [Change default viewing format] | |
No pathways have been reviewed or authored by UniProt:O80786 MCM5 (1600994)
