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Details on Person UniProt:O82387 CDC6
| Class:Id | ReferenceGeneProduct:1600911 |
|---|---|
| _chainChangeLog | chain:1-539 added on Fri May 8 2015 |
| _displayName | UniProt:O82387 CDC6 |
| _timestamp | 2024-08-09 18:41:15 |
| chain | chain:1-539 |
| checksum | 4D44B3BCEDC6E184 |
| comment | FUNCTION May be involved in the initiation of DNA replication. May play a role in endoreduplication. Could act as one of the factors that contributes to maintain endoreduplication competence.SUBCELLULAR LOCATION Highly expressed in roots, flower buds and etiolated seedlings. Expressed in leaves and stems (PubMed:11604464). Highly expressed in proliferating cells such as root meristems, leaf primordia and young growing leaves, as well as cells undergoing endoreduplication cycles (PubMed:11752380).INDUCTION Cell cycle regulated. Up-regulated at the G1/S phase transition and then decreases rapidly as cells progress into S-phase (PubMed:11669580, PubMed:11752380). Degraded in a proteasome-dependent manner in proliferating cells, but not in endoreduplicating cells (PubMed:11752380).MISCELLANEOUS Cells expressing ectopically CDC6 have increased levels of endopolyploidy.SIMILARITY Belongs to the CDC6/cdc18 family. |
| created | [InstanceEdit:1597970] Couchman, M, 2007-07-03 |
| crossReference | [DatabaseIdentifier:1599758] ATIDB:At2g29680 [DatabaseIdentifier:1600105] TAIR:At2g29680 [DatabaseIdentifier:1600106] MIPS:At2g29680 [DatabaseIdentifier:1600107] NCBI Entrez Gene:At2g29680 [DatabaseIdentifier:1600106] MIPS:At2g29680 [DatabaseIdentifier:1600107] NCBI Entrez Gene:At2g29680 [DatabaseIdentifier:1600108] TIGR:At2g29680 [DatabaseIdentifier:1600108] TIGR:At2g29680 |
| description | recommendedName: fullName evidence="7"Cell division control protein 6 homolog shortName evidence="6"AtCDC6 shortName evidence="7"AtCDC6A shortName evidence="5"Cdc6At shortName evidence="7"Cell division control protein 6 homolog A |
| geneName | CDC6 At2g29680 |
| identifier | O82387 |
| isSequenceChanged | FALSE |
| keyword | Alternative splicing Cell cycle Cell division DNA replication Nucleus Reference proteome |
| modified | [InstanceEdit:1598234] Couchman, MS [InstanceEdit:1601927] Preece, J, 2011-09-12 [InstanceEdit:5691543] Weiser, JD [InstanceEdit:9037114] Weiser, JD [InstanceEdit:9637257] Weiser, JD [InstanceEdit:9676415] Weiser, JD [InstanceEdit:9750299] Weiser, JD [InstanceEdit:9852000] Weiser, Joel, 2023-11-03 [InstanceEdit:9917590] Weiser, Joel, 2024-08-09 |
| name | CDC6 |
| otherIdentifier | O82387_ARATH O82387 Q94CM2_ARATH Q94CM2 266616_at AT2G29680 |
| referenceDatabase | [ReferenceDatabase:2] UniProt |
| secondaryIdentifier | CDC6A_ARATH Q94CM2 Q94G54 |
| sequenceLength | 539 |
| species | [Species:170905] Arabidopsis thaliana |
| (isoformParent) | [ReferenceIsoform:8966495] UniProt:O82387-1 CDC6 [Arabidopsis thaliana] [ReferenceIsoform:8966496] UniProt:O82387-2 CDC6 [Arabidopsis thaliana] |
| (referenceEntity) | [EntityWithAccessionedSequence:1599187] cdc6a (gene) [nucleoplasm] [Arabidopsis thaliana] [EntityWithAccessionedSequence:1599245] CDC6a [nucleoplasm] [Arabidopsis thaliana] |
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No pathways have been reviewed or authored by UniProt:O82387 CDC6 (1600911)
