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Details on Person UniProt:Q84LH8 PIF5
| Class:Id | ReferenceGeneProduct:1600859 |
|---|---|
| _chainChangeLog | chain:1-444 added on Fri February 6 2015 |
| _displayName | UniProt:Q84LH8 PIF5 |
| _timestamp | 2024-02-26 03:50:18 |
| chain | chain:1-444 |
| checksum | 593D72C1F2ED86C7 |
| comment | FUNCTION Transcription factor acting negatively in the phytochrome B signaling pathway to promote the shade-avoidance response. Regulates PHYB abundance at the post-transcriptional level, possibly via the ubiquitin-proteasome pathway. Promotes ethylene activity in the dark. May regulate the expression of a subset of genes by binding to the G-box motif. Might be involved in the integration of light-signals to control both circadian and photomorphogenic processes. Activated by CRY1 and CRY2 in response to low blue light (LBL) by direct binding at chromatin on E-box variant 5'-CA[CT]GTG-3' to stimulate specific gene expression to adapt global physiology (e.g. hypocotyl elongation in low blue light) (PubMed:26724867).SUBUNIT Homodimer (By similarity). Interacts specifically with the Pfr form of phytochrome B and with TOC1/APRR1. May form a heterodimer with PIF3. Interacts with PHYB, CRY1 and CRY2 in the nucleus in response to low blue light (LBL) (PubMed:26724867). Interacts with TOPP4 (PubMed:26704640). Associates to PTAC12/HMR/PAP5 which acts as a transcriptional coactivator (PubMed:25944101).INTERACTION Mainly expressed in leaves and seedlings, and, to a lower extent, in stems, fruits, flowers and roots.DEVELOPMENTAL STAGE Circadian-controlled expression (PubMed:15356333). Expressed transiently in early developing seeds, later accumulates progressively in maturating seeds to reach a peak in dry seeds (PubMed:23708772). Fades out upon seed imbibition (PubMed:23708772).INDUCTION Down-regulated by brassinolids (BL), but up-regulated by cold (PubMed:23708772). Follows a free-running robust circadian rhythm, with higher levels during the light phase (PubMed:23708772). Rapidly induced by light in etiolated plants. Up-regulated by white light. Rapid degradation after red light exposure (at protein level). Accumulates to high levels in the dark, is selectively degraded in response to red light and remains at high levels under shade-mimicking conditions.DOMAIN The active phytochrome binding (APB) motif (26-39) is involved in interaction with PHYB and is required for proteasome-mediated degradation.PTM Phosphorylated. Additional phosphorylations induced within 60 seconds following phytochrome B photoactivation.PTM Dephosphorylated by TOPP4 during photomorphogenesis, leading to subsequent degradation of PIF5 by the proteasomal pathway.MISCELLANEOUS May be due to a competing acceptor splice site.MISCELLANEOUS May be due to a competing acceptor splice site. |
| created | [InstanceEdit:1601927] Preece, J, 2011-09-12 |
| description | recommendedName: fullName evidence="20"Transcription factor PIF5 alternativeName: fullName evidence="16"Basic helix-loop-helix protein 65 shortName evidence="16"AtbHLH65 shortName evidence="16"bHLH 65 alternativeName: fullName evidence="17"Phytochrome interacting factor-like 6 alternativeName: fullName evidence="20"Phytochrome-interacting factor 5 alternativeName: fullName evidence="18"Transcription factor EN 103 alternativeName: fullName evidence="16"bHLH transcription factor bHLH065 |
| geneName | PIF5 BHLH65 EN103 PIL6 At3g59060 F17J16.110 |
| identifier | Q84LH8 |
| isSequenceChanged | FALSE |
| keyword | Alternative splicing DNA-binding Nucleus Phosphoprotein Phytochrome signaling pathway Reference proteome Transcription Transcription regulation |
| modified | [InstanceEdit:1598234] Couchman, MS [InstanceEdit:1995863] Weiser, JD [InstanceEdit:2132304] Weiser, JD [InstanceEdit:2265580] Weiser, JD [InstanceEdit:2587579] Weiser, JD [InstanceEdit:5433710] Weiser, JD [InstanceEdit:5634237] Weiser, JD [InstanceEdit:5673015] Weiser, JD [InstanceEdit:9037114] Weiser, JD [InstanceEdit:9637257] Weiser, JD [InstanceEdit:9676415] Weiser, JD [InstanceEdit:9852000] Weiser, Joel, 2023-11-03 [InstanceEdit:9862192] Weiser, Joel, 2024-02-26 |
| name | PIF5 |
| otherIdentifier | AT3G59060 Q84LH8 Q84LH8_ARATH |
| referenceDatabase | [ReferenceDatabase:2] UniProt |
| secondaryIdentifier | PIF5_ARATH Q8RXG4 Q8S3D7 Q9LYT0 |
| sequenceLength | 444 |
| species | [Species:170905] Arabidopsis thaliana |
| (isoformParent) | [ReferenceIsoform:8976687] UniProt:Q84LH8-1 PIF5 [Arabidopsis thaliana] [ReferenceIsoform:8976688] UniProt:Q84LH8-2 PIF5 [Arabidopsis thaliana] [ReferenceIsoform:8976689] UniProt:Q84LH8-3 PIF5 [Arabidopsis thaliana] |
| (referenceEntity) | [EntityWithAccessionedSequence:1599108] PIF5 [nucleoplasm] [Arabidopsis thaliana] [EntityWithAccessionedSequence:1599291] phospho-PIF5 [nucleoplasm] [Arabidopsis thaliana] |
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No pathways have been reviewed or authored by UniProt:Q84LH8 PIF5 (1600859)
