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Details on Person GINS complex interacts stably with MCM2-7 and CDC45 at the replication fork

Class:Id	Reaction:1598988
_displayName	GINS complex interacts stably with MCM2-7 and CDC45 at the replication fork
_doRelease	TRUE
_timestamp	2016-07-15 23:50:50
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:1598018] Tsesmetzis, N, 2007-06-22
input	[Complex:1599606] GINS complex [nucleoplasm] [Arabidopsis thaliana] [Complex:1599577] MCM2-7:MCM8 [nucleoplasm] [Arabidopsis thaliana] [EntityWithAccessionedSequence:1599408] CDC45 [nucleoplasm] [Arabidopsis thaliana]
literatureReference	[LiteratureReference:1600739] Genome-wide Analysis of the Core DNA Replication Machinery in the Higher Plants Arabidopsis and Oryza sativa
modified	[InstanceEdit:1597986] Tsesmetzis, N, 2007-06-26 [InstanceEdit:1597954] Tsesmetzis, N, 2007-06-27 [InstanceEdit:1597743] Tsesmetzis, N, 2007-06-28 [InstanceEdit:1597927] Tsesmetzis, N, 2007-06-28 [InstanceEdit:1597800] Tsesmetzis, N, 2007-06-29 [InstanceEdit:1598015] Tsesmetzis, N, 2007-07-10 [InstanceEdit:1598003] Tsesmetzis, N, 2007-07-24 [InstanceEdit:1597738] Higgins, JA, 2007-07-27 [InstanceEdit:1597961] Higgins, JA, 2009-03-05 [InstanceEdit:1597787] Higgins, JA, 2009-03-05 [InstanceEdit:1597843] Higgins, JA, 2009-03-05 [InstanceEdit:1597980] Higgins, JA, 2009-04-09 [InstanceEdit:1598200] Couchman, MS [InstanceEdit:1597888] Couchman, MS [InstanceEdit:1597889] Couchman, MS [InstanceEdit:1597952] Couchman, MS [InstanceEdit:1598112] Couchman, MS [InstanceEdit:1598108] Couchman, MS [InstanceEdit:1597958] Couchman, MS [InstanceEdit:1598158] Couchman, MS [InstanceEdit:1601927] Preece, J, 2011-09-12 [InstanceEdit:2671767] D'Eustachio, P, 2012-11-24 [InstanceEdit:8879177] Wu, G, 2016-07-15 [InstanceEdit:9034313] D'Eustachio, Peter, 2018-01-03
name	GINS complex interacts stably with MCM2-7 and CDC45 at the replication fork
output	[Complex:1599569] CDC45:GINS:MCM2-7:MCM8 [nucleoplasm] [Arabidopsis thaliana]
precedingEvent	[Reaction:1598878] CDC45 associates with the pre-replicative complex at the origin [Arabidopsis thaliana] [Reaction:1598973] CDT1 is released from the pre-replication complex causing MCM2-7 loading around the DNA [Arabidopsis thaliana] [Reaction:1598872] Formation of GINS complex [Arabidopsis thaliana]
reviewed	[InstanceEdit:1598136] Doonan, JH, 2007-11-10
species	[Species:170905] Arabidopsis thaliana
stableIdentifier	[StableIdentifier:8929877] R-ATH-1598988.1
summation	[Summation:1598417] The GINS complex is a core component of the eukaryotic DNA r...
(hasEvent)	[Pathway:1598633] Unwinding of DNA [Arabidopsis thaliana]
(precedingEvent)	[Reaction:1598877] The GINS:MCM2-7:MCM8:CDC45 components of the activated pre-replicative complex cause unwinding of the replication fork [Arabidopsis thaliana]
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