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Details on Person CDT1 is released from the pre-replication complex causing MCM2-7 loading around the DNA

Class:Id	Reaction:1598973
_displayName	CDT1 is released from the pre-replication complex causing MCM2-7 loading around the DNA
_doRelease	TRUE
_timestamp	2016-07-15 23:50:23
authored	[InstanceEdit:1598211] Tsesmetzis, N, Higgins, JA, 2007-07-25
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:1597978] Tsesmetzis, N, 2007-06-22
input	[Complex:1599653] MCM8-10:pre-replicative complex [nucleoplasm] [Arabidopsis thaliana]
literatureReference	[LiteratureReference:1600739] Genome-wide Analysis of the Core DNA Replication Machinery in the Higher Plants Arabidopsis and Oryza sativa
modified	[InstanceEdit:1598179] Tsesmetzis, N, 2007-06-28 [InstanceEdit:1598191] Tsesmetzis, N, 2007-07-10 [InstanceEdit:1598015] Tsesmetzis, N, 2007-07-10 [InstanceEdit:1598003] Tsesmetzis, N, 2007-07-24 [InstanceEdit:1597738] Higgins, JA, 2007-07-27 [InstanceEdit:1597842] Higgins, JA, 2009-03-05 [InstanceEdit:1598200] Couchman, MS [InstanceEdit:1597888] Couchman, MS [InstanceEdit:1597889] Couchman, MS [InstanceEdit:1597958] Couchman, MS [InstanceEdit:1601927] Preece, J, 2011-09-12 [InstanceEdit:2671767] D'Eustachio, P, 2012-11-24 [InstanceEdit:8879177] Wu, G, 2016-07-15
name	CDT1 is released from the pre-replication complex causing MCM2-7 loading around the DNA
output	[CandidateSet:1599516] CDT1 [nucleoplasm] [Arabidopsis thaliana] [Complex:1599615] MCM2-7:CDC6:NOC3:ORC:origin [nucleoplasm] [Arabidopsis thaliana]
precedingEvent	[Reaction:1598773] MCM2-7 associate with the CDT1:CDC6:ORC:origin complex, forming the pre-replicative complex (pre-RC) [Arabidopsis thaliana] [Reaction:1598763] CDT1 associates with the CDC6:NOC3:ORC:origin complex [Arabidopsis thaliana] [Reaction:1598739] Transcription of mcm3 gene by E2Fa/b:DPa complex [Arabidopsis thaliana] [Reaction:1598736] MCM8, MCM9 and MCM10 associate with the pre-replicative complex stabilizing MCM2-7 [Arabidopsis thaliana] [Reaction:1598763] CDT1 associates with the CDC6:NOC3:ORC:origin complex [Arabidopsis thaliana]
reviewed	[InstanceEdit:1598136] Doonan, JH, 2007-11-10
species	[Species:170905] Arabidopsis thaliana
stableIdentifier	[StableIdentifier:8919217] R-ATH-1598973.1
summation	[Summation:1598411] This event is the result of the ATP hydrolysis by ORC/CDC6
(hasEvent)	[Pathway:1598607] Activation of the pre-replicative complex [Arabidopsis thaliana]
(precedingEvent)	[Reaction:1598878] CDC45 associates with the pre-replicative complex at the origin [Arabidopsis thaliana]
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No pathways have been reviewed or authored by CDT1 is released from the pre-replication complex causing MCM2-7 loading around the DNA (1598973)