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Details on Person CDC45 associates with the pre-replicative complex at the origin

Class:Id	Reaction:1598878
_displayName	CDC45 associates with the pre-replicative complex at the origin
_doRelease	TRUE
_timestamp	2016-07-15 23:48:58
authored	[InstanceEdit:1598211] Tsesmetzis, N, Higgins, JA, 2007-07-25
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:1597921] Tsesmetzis, N, 2007-06-21
input	[EntityWithAccessionedSequence:1599408] CDC45 [nucleoplasm] [Arabidopsis thaliana] [Complex:1599653] MCM8-10:pre-replicative complex [nucleoplasm] [Arabidopsis thaliana]
literatureReference	[LiteratureReference:1600739] Genome-wide Analysis of the Core DNA Replication Machinery in the Higher Plants Arabidopsis and Oryza sativa
modified	[InstanceEdit:1597978] Tsesmetzis, N, 2007-06-22 [InstanceEdit:1597986] Tsesmetzis, N, 2007-06-26 [InstanceEdit:1598179] Tsesmetzis, N, 2007-06-28 [InstanceEdit:1598015] Tsesmetzis, N, 2007-07-10 [InstanceEdit:1598003] Tsesmetzis, N, 2007-07-24 [InstanceEdit:1597738] Higgins, JA, 2007-07-27 [InstanceEdit:1597842] Higgins, JA, 2009-03-05 [InstanceEdit:1597985] Higgins, JA, 2009-03-05 [InstanceEdit:1598200] Couchman, MS [InstanceEdit:1597888] Couchman, MS [InstanceEdit:1597889] Couchman, MS [InstanceEdit:1597952] Couchman, MS [InstanceEdit:1598112] Couchman, MS [InstanceEdit:1597958] Couchman, MS [InstanceEdit:1598158] Couchman, MS [InstanceEdit:1601927] Preece, J, 2011-09-12 [InstanceEdit:2671767] D'Eustachio, P, 2012-11-24 [InstanceEdit:8879177] Wu, G, 2016-07-15
name	CDC45 associates with the pre-replicative complex at the origin
output	[Complex:1599639] CDC45:MCM8-10:pre-replicative complex [nucleoplasm] [Arabidopsis thaliana]
precedingEvent	[Reaction:1598973] CDT1 is released from the pre-replication complex causing MCM2-7 loading around the DNA [Arabidopsis thaliana] [Reaction:1598773] MCM2-7 associate with the CDT1:CDC6:ORC:origin complex, forming the pre-replicative complex (pre-RC) [Arabidopsis thaliana] [Reaction:1598736] MCM8, MCM9 and MCM10 associate with the pre-replicative complex stabilizing MCM2-7 [Arabidopsis thaliana]
reviewed	[InstanceEdit:1598136] Doonan, JH, 2007-11-10
species	[Species:170905] Arabidopsis thaliana
stableIdentifier	[StableIdentifier:8881675] R-ATH-1598878.1
summation	[Summation:1598432] CDC45 is required for the initiation of DNA replication in y...
(hasEvent)	[Pathway:1598607] Activation of the pre-replicative complex [Arabidopsis thaliana]
(precedingEvent)	[Reaction:1598869] DNA Replication Factor A (RPA) associates with the pre-replicative complex at the origin [Arabidopsis thaliana] [Reaction:1598988] GINS complex interacts stably with MCM2-7 and CDC45 at the replication fork [Arabidopsis thaliana]
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No pathways have been reviewed or authored by CDC45 associates with the pre-replicative complex at the origin (1598878)