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Details on Person In the sequestration model, the Mad2 molecules that dissocia...
| Class:Id | Summation:1598574 |
|---|---|
| _displayName | In the sequestration model, the Mad2 molecules that dissocia... |
| _timestamp | 2011-09-12 23:26:25 |
| created | [InstanceEdit:1597865] Higgins, JA, 2007-11-15 |
| modified | [InstanceEdit:1601927] Preece, J, 2011-09-12 |
| text | In the sequestration model, the Mad2 molecules that dissociate from unattached kinetochores are perceived to bind to Cdc20, a protein that recruits specific substrates to the APC/C. Consequently, Mad2 indirectly inhibits the APC/C by sequestering its activator, Cdc20. This requires interaction between Mad1 and Mad2. Cdc20 and Mad1 bind to the same site on Mad2. (imported from Human Reactome, Stable identifier: REACT_4333.2) |
| (summation) | [Reaction:1598931] Inactivation of APC/C via CDC20 sequestration [Arabidopsis thaliana] |
| [Change default viewing format] | |
No pathways have been reviewed or authored by In the sequestration model, the Mad2 molecules that dissocia... (1598574)
