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Details on Person Ronceret et al., 2005 reported two arabidopsis genes encodin...

Class:IdSummation:1598571
_displayNameRonceret et al., 2005 reported two arabidopsis genes encodin...
_timestamp2011-09-12 23:26:25
created[InstanceEdit:1597867] Tsesmetzis, N, 2007-06-29
literatureReference[LiteratureReference:1600626] Genetic analysis of two Arabidopsis DNA polymerase epsilon subunits during early embryogenesis
[LiteratureReference:1600755] Interactions between the cell cycle and embryonic patterning in Arabidopsis uncovered by a mutation in DNA polymerase epsilon
[LiteratureReference:1600739] Genome-wide Analysis of the Core DNA Replication Machinery in the Higher Plants Arabidopsis and Oryza sativa
modified[InstanceEdit:1597767] Higgins, JA, 2007-10-19
[InstanceEdit:1601927] Preece, J, 2011-09-12
textRonceret et al., 2005 reported two arabidopsis genes encoding the catalytic subunit POLE1 (POLE1A and POLE1B). They also reported a single gene encoding the second largest subunit (POLE2). Both POLE1A and POLE1B were shown to contain the conserved domains of other eukaryotic homologs. POLE1A or POLE2 mutants had DNA replication defects, while POLE1B mutants do not exhibit visible phenotypic effects (Ronceret et al., 2005). POLE1A/B double mutants, however, arrest earlier than single POLE1A mutants, suggesting some functional overlap in vivo (Jenik et al., 2005). No POLE3 and POLE4 homologs have been found in arabidopsis.
(summation)[Reaction:1598797] DNA polymerase epsilon (POLE) binds at the origin [Arabidopsis thaliana]
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