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Details on Person Plant topoisomerase II and VI play distinct and overlapping ...

Class:IdSummation:1598550
_displayNamePlant topoisomerase II and VI play distinct and overlapping ...
_timestamp2011-09-12 23:26:25
created[InstanceEdit:1598111] Higgins, JA, 2007-07-25
literatureReference[LiteratureReference:1600610] Endoreduplication and activation of the anaphase-promoting complex during symbiotic cell development
[LiteratureReference:1600795] DNA topoisomerase VI is essential for endoreduplication in Arabidopsis
modified[InstanceEdit:1597738] Higgins, JA, 2007-07-27
[InstanceEdit:1598035] Higgins, JA, 2007-11-02
[InstanceEdit:1598047] Higgins, JA, 2008-01-21
[InstanceEdit:1601927] Preece, J, 2011-09-12
textPlant topoisomerase II and VI play distinct and overlapping roles during the mitotic cell cycle and the endocycle. Endocycles are composed of an S-phase and a gap phase. However the mechanisms and signals required for the initiation and maintenance of endocycles are largely unknown. Polyploidy, usually in the range of 4C to 64C DNA, can occur in any tissue or organ and is regulated by a variety of tissue specific mechanisms. DNA Topoisomerase VI is required in endocycles beyond 8C. This has been demonstrated in two extreme dwarf mutants, hypocotyl6 (hyp6) and root hairless2 (rhl2).
(summation)[Pathway:1598636] Regulation of DNA endoreduplication by topoisomerases [Arabidopsis thaliana]
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