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Details on Person In vitro structural studies have shown that Mad2 undergoes a...

Class:IdSummation:1598451
_displayNameIn vitro structural studies have shown that Mad2 undergoes a...
_timestamp2011-09-12 23:26:25
created[InstanceEdit:1597857] Higgins, JA, 2007-11-15
modified[InstanceEdit:1598195] Higgins, JA, 2009-03-05
[InstanceEdit:1601927] Preece, J, 2011-09-12
textIn vitro structural studies have shown that Mad2 undergoes a major conformational change upon binding to Mad1. This conformational change is postulated to activate Mad2 into a high affinity state which can bind and sequester Cdc20 from the APC. (imported from Human Reactome: REACT 2215.1)
(summation)[Reaction:1598965] MAD2 converted to an inhibitory state via interaction with Mad1 [Arabidopsis thaliana]
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No pathways have been reviewed or authored by In vitro structural studies have shown that Mad2 undergoes a... (1598451)