Query author contributions in Reactome
Reactome depends on collaboration between our curation team and outside experts to assemble and peer-review its pathway modules. The integration of ORCID within Reactome enables us to meet a key challenge with authoring, curating and reviewing biological information by incentivizing and crediting the external experts that contribute their expertise and time to the Reactome curation process. More information is available at ORCID and Reactome.
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Details on Person The remaining flap, which is too short to support RPA bindin...
| Class:Id | Summation:1598446 |
|---|---|
| _displayName | The remaining flap, which is too short to support RPA bindin... |
| _timestamp | 2011-09-12 23:26:25 |
| created | [InstanceEdit:1597807] Tsesmetzis, N, 2007-06-27 |
| modified | [InstanceEdit:1597800] Tsesmetzis, N, 2007-06-29 [InstanceEdit:1601927] Preece, J, 2011-09-12 |
| text | The remaining flap, which is too short to support RPA binding, is then processed by FEN1. There is evidence that binding of RPA to the displaced end of the RNA-containing Okazaki fragment prevents FEN1 from accessing the substrate. FEN1 is a structure-specific endonuclease that cleaves near the base of the flap at a position one nucleotide into the annealed region. Biochemical studies have shown that the preferred substrate for FEN1 consists of a one-nucleotide 3'-tail on the upstream primer in addition to the 5'-flap of the downstream primer. (imported from Human Reactome Stable identifier: REACT_2024.1) |
| (summation) | [Reaction:1598964] Removal of remaining flap [Arabidopsis thaliana] |
| [Change default viewing format] | |
No pathways have been reviewed or authored by The remaining flap, which is too short to support RPA bindin... (1598446)
